Genome-wide association study identifies eight loci associated with blood pressure

…, SM Schwartz, DS Siscovick, I Subirana… - Nature …, 2009 - nature.com
Elevated blood pressure is a common, heritable cause of cardiovascular disease worldwide.
To date, identification of common genetic variants influencing blood pressure has proven …

Remnant cholesterol, not LDL cholesterol, is associated with incident cardiovascular disease

O Castañer, X Pintó, I Subirana, AJ Amor, E Ros… - Journal of the American …, 2020 - jacc.org
Background Genetic, observational, and clinical intervention studies indicate that circulating
levels of triglycerides and cholesterol transported in triglyceride-rich lipoproteins (remnant …

Validity of an adaptation of the Framingham cardiovascular risk function: the VERIFICA Study

J Marrugat, I Subirana, E Comín, C Cabezas… - … of Epidemiology & …, 2007 - jech.bmj.com
Background: To assess the reliability and accuracy of the Framingham coronary heart disease
(CHD) risk function adapted by the Registre Gironí del Cor (REGICOR) investigators in …

Risk of cause-specific death in individuals with diabetes: a competing risks analysis

JM Baena-Díez, J Peñafiel, I Subirana, R Ramos… - Diabetes …, 2016 - Am Diabetes Assoc
OBJECTIVE Diabetes is a common cause of shortened life expectancy. We aimed to assess
the association between diabetes and cause-specific death. RESEARCH DESIGN AND …

Building bivariate tables: the compareGroups package for R

I Subirana, H Sanz, J Vila - Journal of statistical software, 2014 - jstatsoft.org
The R package compareGroups provides functions meant to facilitate the construction of
bivariate tables (descriptives of several variables for comparison between groups) and …

Trends in cardiovascular risk factor prevalence (1995-2000-2005) in northeastern Spain

M Grau, I Subirana, R Elosua, P Solanas… - European Journal of …, 2007 - academic.oup.com
Background High prevalence of cardiovascular risk factors has been observed in Spain
along with low incidence of acute myocardial infarction. Our objective was to determine the …

Meta-analyses of the association between cytochrome CYP2C19 loss-and gain-of-function polymorphisms and cardiovascular outcomes in patients with coronary …

M Zabalza, I Subirana, J Sala, C Lluis-Ganella… - Heart, 2012 - heart.bmj.com
Aims To perform a meta-analysis of the association between CYP2C19 loss- and gain-of-function
variants and cardiovascular outcomes and bleeding in patients with coronary artery …

Olive oil polyphenols enhance high-density lipoprotein function in humans: a randomized controlled trial

…, M Farràs, Ú Catalán, I Subirana… - … and Vascular Biology, 2014 - Am Heart Assoc
Objective— Olive oil polyphenols have shown beneficial properties against cardiovascular
risk factors. Their consumption has been associated with higher cholesterol content in high-…

Polymorphisms in the NOS1APGene Modulate QT Interval Duration and Risk of Arrhythmias in the Long QT Syndrome

…, C Napolitano, L De Giuli, R Bloise, I Subirana… - Journal of the American …, 2010 - jacc.org
Objectives : We investigated the role of nitric oxide 1 adaptor protein (NOS1AP) as a genetic
modifier of long QT syndrome (LQTS). Background : LQTS risk stratification is complicated …

Effect of virgin olive oil and thyme phenolic compounds on blood lipid profile: Implications of human gut microbiota

…, N Pizarro, M Farràs, R De la Torre, I Subirana… - European journal of …, 2017 - Springer
Purpose To investigate the effect of virgin olive oil phenolic compounds (PC) alone or in
combination with thyme PC on blood lipid profile from hypercholesterolemic humans, and …