Natural contamination with arsenic and other toxic trace elements was studied on a 50,000
km (2) area of the Pampean Plain in Argentina. The locations where natural sources of …

We explore the risk that network attackers can exploit unauthenticated Network Time Protocol
(NTP) traffic to alter the time on client systems. We first discuss how an on-path attacker, …

Genome sequencing has established clinical utility for rare disease diagnosis. While increasing
numbers of individuals have undergone elective genome sequencing, a comprehensive …

Proton pump inhibitors, PPIs, are widely prescribed and sold globally. Although initially
intended for time-limited treatment of acute disorders, such as gastric ulcers and esophagitis, …

Antibodies targeting the PD-1, PD-L1, and CTLA-4 immune checkpoint axis have been used
in a variety of tumor types. They achieve anti-tumor activity through activating the patient’s …

Background Modern medicine is rapidly moving towards a data-driven paradigm based on
comprehensive multimodal health assessments. Integrated analysis of data from different …

Background Acetaminophen (paracetamol) is one of the most common medications used for
management of pain in the world. There is lack of consensus about the mechanism of action…

Current therapeutic approaches to depression fail for millions of patients due to lag in clinical
response and non-adherence. Here we provide new support for the antidepressant effect …

3,4-Methylenedioxymethamphetamine (MDMA) is currently being evaluated by the Food
and Drug Administration (FDA) for the treatment of post-traumatic stress disorder (PTSD). If …

Before pulsed power systems can be fielded in either mobile or small footprint stationary
applications, the prime power source must be optimized for both size and operational efficiency. …