Paramutation is a heritable epigenetic modification induced in plants by cross-talk between
allelic loci. Here we report a similar modification of the mouse Kit gene in the progeny of …

Propagating Ca 2+ waves are a characteristic feature of Ca 2+ -linked signal transduction
pathways. Intracellular Ca 2+ waves are formed by regenerative stimulation of Ca 2+ release …

Sex differentiation is a unique developmental process. Starting from a bipotential gonad, it
gives rise to the ovary and the testis, two highly specialized organs that differ morphologically …

The CD36 scavenger receptor is involved in the uptake and transport of fatty acids, as well
as the phagocytosis process in macrophages. We show here that the CD36 protein is …

Nutritional long-chain fatty acids control adipose tissue mass by regulating the number and
the size of adipocytes. It is now established that peroxisome-proliferator-activated receptors (…

In many species, fertilization triggers a wave of cortical granule exocytosis in the egg that is
the consequence of an increase in intracellular free calcium concentration. We have …

Mural trophectoderm cells of the mouse embryo possess a phagocytic potential as early as
3.5 days post coitum (dpc). This first differentiated function shows a graded variation along …

The fertilisation calcium wave in sea urchin eggs triggers the onset of development. The wave
is an explosive increase in intracellular free calcium concentration that begins at the point …

In mammals, testicular differentiation is initiated by transcription factors SRY and SOX9 in
XY gonads, and ovarian differentiation involves R-spondin1 (RSPO1) mediated activation of …

Sea urchin eggs and those of most other deuterostomes are activated at fertilization by an
increase in cytoplasmic free calcium concentration ([Ca 2+ ] i ) that triggers the onset of the …