Trypanosoma cruzi invades most nucleated cells by a mechanism distinct from classical
phagocytosis. Although parasites enter at the lysosome-poor peripheral cell margins, lysosomal …

Apicomplexa are obligate intracellular parasites that actively invade host cells using their
membrane-associated, actin-myosin motor. The current view is that host cell invasion by …

The protozoan parasite Toxoplasma gondii has co-evolved with its homeothermic hosts (humans
included) strategies that drive its quasi-asymptomatic persistence in hosts, hence …

The protozoan parasite Toxoplasma gondii enters hosts through the intestinal mucosa and
colonizes distant tissues such as the brain, where its progeny persists for a lifetime. We …

Streptococcus agalactiae (group B streptococcus; GBS) is a normal constituent of the intestinal
microflora and the major cause of human neonatal meningitis. A single clone, GBS ST-17…

Toxoplasma gondii, the causative agent of toxoplasmosis, is an obligate intracellular protozoan
parasite that resides inside a parasitophorous vacuole. During infection, Toxoplasma …

An early hallmark of Toxoplasma gondii infection is the rapid control of the parasite population
by a potent multifaceted innate immune response that engages resident and homing …

Apicomplexan parasites invade host cells by forming a ring-like junction with the cell surface
and actively sliding through the junction inside an intracellular vacuole. Apical membrane …

Apicomplexan parasites are thought to actively invade the host cell by gliding motility. This
movement is powered by the parasite's own actomyosin system, and depends on the …

During invasion, apicomplexan parasites form an intimate circumferential contact with the
host cell, the tight junction (TJ), through which they actively glide. The TJ, which links the …