[PDF][PDF] Lysosome recruitment and fusion are early events required for trypanosome invasion of mammalian cells
I Tardieux, P Webster, J Ravesloot, W Boron, JA Lunn… - Cell, 1992 - cell.com
Trypanosoma cruzi invades most nucleated cells by a mechanism distinct from classical
phagocytosis. Although parasites enter at the lysosome-poor peripheral cell margins, lysosomal …
phagocytosis. Although parasites enter at the lysosome-poor peripheral cell margins, lysosomal …
[PDF][PDF] Host cell entry by apicomplexa parasites requires actin polymerization in the host cell
…, C Leroy, S Blazquez, R Menard, I Tardieux - Cell host & …, 2009 - cell.com
Apicomplexa are obligate intracellular parasites that actively invade host cells using their
membrane-associated, actin-myosin motor. The current view is that host cell invasion by …
membrane-associated, actin-myosin motor. The current view is that host cell invasion by …
The Toxoplasma effector TEEGR promotes parasite persistence by modulating NF-κB signalling via EZH2
…, V Josserand, B Touquet, Y Couté, I Tardieux… - Nature …, 2019 - nature.com
The protozoan parasite Toxoplasma gondii has co-evolved with its homeothermic hosts (humans
included) strategies that drive its quasi-asymptomatic persistence in hosts, hence …
included) strategies that drive its quasi-asymptomatic persistence in hosts, hence …
CD11c- and CD11b-expressing mouse leukocytes transport single Toxoplasma gondii tachyzoites to the brain
…, P Sonigo, G Milon, D Buzoni-Gâtel, I Tardieux - Blood, 2006 - ashpublications.org
The protozoan parasite Toxoplasma gondii enters hosts through the intestinal mucosa and
colonizes distant tissues such as the brain, where its progeny persists for a lifetime. We …
colonizes distant tissues such as the brain, where its progeny persists for a lifetime. We …
The surface protein HvgA mediates group B streptococcus hypervirulence and meningeal tropism in neonates
…, MY Mistou, H Khun, C Mechler, I Tardieux… - Journal of experimental …, 2010 - rupress.org
Streptococcus agalactiae (group B streptococcus; GBS) is a normal constituent of the intestinal
microflora and the major cause of human neonatal meningitis. A single clone, GBS ST-17…
microflora and the major cause of human neonatal meningitis. A single clone, GBS ST-17…
A Toxoplasma dense granule protein, GRA24, modulates the early immune response to infection by promoting a direct and sustained host p38 MAPK activation
…, Y Coute, H Pelloux, I Tardieux… - Journal of Experimental …, 2013 - rupress.org
Toxoplasma gondii, the causative agent of toxoplasmosis, is an obligate intracellular protozoan
parasite that resides inside a parasitophorous vacuole. During infection, Toxoplasma …
parasite that resides inside a parasitophorous vacuole. During infection, Toxoplasma …
Toxoplasma gondii TgIST co-opts host chromatin repressors dampening STAT1-dependent gene regulation and IFN-γ–mediated host defenses
…, B Touquet, PJ De Bock, Y Coute, I Tardieux… - Journal of Experimental …, 2016 - rupress.org
An early hallmark of Toxoplasma gondii infection is the rapid control of the parasite population
by a potent multifaceted innate immune response that engages resident and homing …
by a potent multifaceted innate immune response that engages resident and homing …
[HTML][HTML] Apical membrane antigen 1 mediates apicomplexan parasite attachment but is dispensable for host cell invasion
…, V Lagal, S Thiberge, JA Whitelaw, I Tardieux… - Nature …, 2013 - nature.com
Apicomplexan parasites invade host cells by forming a ring-like junction with the cell surface
and actively sliding through the junction inside an intracellular vacuole. Apical membrane …
and actively sliding through the junction inside an intracellular vacuole. Apical membrane …
[HTML][HTML] The toxoplasma Acto-MyoA motor complex is important but not essential for gliding motility and host cell invasion
…, G Pall, JA Black, DJP Ferguson, I Tardieux… - PloS one, 2014 - journals.plos.org
Apicomplexan parasites are thought to actively invade the host cell by gliding motility. This
movement is powered by the parasite's own actomyosin system, and depends on the …
movement is powered by the parasite's own actomyosin system, and depends on the …
[PDF][PDF] Independent roles of apical membrane antigen 1 and rhoptry neck proteins during host cell invasion by apicomplexa
…, A Combe, S Thiberge, P Baldacci, I Tardieux… - Cell host & …, 2011 - cell.com
During invasion, apicomplexan parasites form an intimate circumferential contact with the
host cell, the tight junction (TJ), through which they actively glide. The TJ, which links the …
host cell, the tight junction (TJ), through which they actively glide. The TJ, which links the …