Arthritis provoked by linked T and B cell recognition of a glycolytic enzyme
I Matsumoto, A Staub, C Benoist, D Mathis - Science, 1999 - science.org
The hallmark of rheumatoid arthritis (RA) is specific destruction of the synovial joints. In a
mouse line that spontaneously develops a disorder with many of the features of human RA, …
mouse line that spontaneously develops a disorder with many of the features of human RA, …
How antibodies to a ubiquitous cytoplasmic enzyme may provoke joint-specific autoimmune disease
I Matsumoto, M Maccioni, DM Lee, M Maurice… - Nature …, 2002 - nature.com
Arthritis in the K/BxN mouse model results from pathogenic immunoglobulins (Igs) that recognize
the ubiquitous cytoplasmic enzyme glucose-6-phosphate isomerase (GPI). But how is a …
the ubiquitous cytoplasmic enzyme glucose-6-phosphate isomerase (GPI). But how is a …
[HTML][HTML] AXL confers intrinsic resistance to osimertinib and advances the emergence of tolerant cells
…, M Boroni, A Yoshimura, S Shiotsu, I Matsumoto… - Nature …, 2019 - nature.com
A novel EGFR-tyrosine kinase inhibitor (TKI), osimertinib, has marked efficacy in patients
with EGFR-mutated lung cancer. However, some patients show intrinsic resistance and an …
with EGFR-mutated lung cancer. However, some patients show intrinsic resistance and an …
[HTML][HTML] Transient IGF-1R inhibition combined with osimertinib eradicates AXL-low expressing EGFR mutated lung cancer
…, I Matsumoto, X Han, K Matsumoto… - Nature …, 2020 - nature.com
Drug tolerance is the basis for acquired resistance to epidermal growth factor receptor-tyrosine
kinase inhibitors (EGFR-TKIs) including osimertinib, through mechanisms that still remain …
kinase inhibitors (EGFR-TKIs) including osimertinib, through mechanisms that still remain …
Long-term effect of thymectomy plus prednisone versus prednisone alone in patients with non-thymomatous myasthenia gravis: 2-year extension of the MGTX …
…, T Nagayasu, M Takamori, M Oda, I Matsumoto… - The Lancet …, 2019 - thelancet.com
Background The Thymectomy Trial in Non-Thymomatous Myasthenia Gravis Patients Receiving
Prednisone (MGTX) showed that thymectomy combined with prednisone was superior …
Prednisone (MGTX) showed that thymectomy combined with prednisone was superior …
[HTML][HTML] Analysis of IgG4 class switch-related molecules in IgG4-related disease
…, Y Kondo, A Tanaka, M Moriyama, I Matsumoto… - Arthritis research & …, 2012 - Springer
Introduction Immunoglobulin G4 (IgG4)-related disease (IgG4-RD) is a new disease entity
characterized by high serum IgG4 levels, IgG4-positive plasmacytic infiltration, and fibrosis in …
characterized by high serum IgG4 levels, IgG4-positive plasmacytic infiltration, and fibrosis in …
Crosstalk to stromal fibroblasts induces resistance of lung cancer to epidermal growth factor receptor tyrosine kinase inhibitors
…, Q Li, T Yamada, K Matsumoto, I Matsumoto… - Clinical Cancer …, 2009 - AACR
Purpose: Lung cancers with epidermal growth factor receptor (EGFR)–activating mutations
show good clinical response to gefitinib and erlotinib, selective tyrosine kinase inhibitors (TKI…
show good clinical response to gefitinib and erlotinib, selective tyrosine kinase inhibitors (TKI…
The STEAP protein family: versatile oxidoreductases and targets for cancer immunotherapy with overlapping and distinct cellular functions
…, H Bach, A Cossarizza, I Matsumoto - Biology of the …, 2012 - Wiley Online Library
The human six‐transmembrane epithelial antigen of the prostate (STEAP) protein family
contains at least five homologous members. The necessity of multiple homologous STEAP …
contains at least five homologous members. The necessity of multiple homologous STEAP …
Long interspersed nuclear element 1 hypomethylation is a marker of poor prognosis in stage IA non–small cell lung cancer
K Saito, K Kawakami, I Matsumoto, M Oda… - Clinical cancer …, 2010 - AACR
Purpose: Global hypomethylation and the hypermethylation of gene promoter regions are
common events in tumor DNA. The aim of this study was to evaluate the prognostic …
common events in tumor DNA. The aim of this study was to evaluate the prognostic …
Segmentectomy for ground-glass-dominant lung cancer with a tumour diameter of 3 cm or less including ground-glass opacity (JCOG1211): a multicentre, single-arm …
…, Y Asato, H Nakayama, I Matsumoto… - The Lancet …, 2023 - thelancet.com
Background Although segmentectomy is a widely used surgical procedure, lobectomy is the
standard procedure for resectable non-small-cell lung cancer (NSCLC). This study aimed to …
standard procedure for resectable non-small-cell lung cancer (NSCLC). This study aimed to …