A safe and effective vaccine against COVID-19 is urgently needed in quantities that are
sufficient to immunize large populations. Here we report the preclinical development of two …

To contain the coronavirus disease 2019 (COVID-19) pandemic, a safe and effective
vaccine against the new severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is …

Initial COVID-19 vaccine candidates were based on the original sequence of SARS-CoV-2.
However, the virus has since accumulated mutations, among which the spike D614G is …

Translational models have played an important role in the rapid development of safe and
effective vaccines and therapeutic agents for the ongoing coronavirus disease 2019 (COVID-19…

Coronavirus disease 2019 (COVID-19) in humans has a wide range of presentations, ranging
from asymptomatic or mild symptoms to severe illness. Suitable animal models mimicking …

Using viral metagenomics we analyzed four bovine serum pools assembled from 715
calves in the United States. Two parvoviruses, bovine parvovirus 2 (BPV2) and a previously …

Genotypes 3 and 4 hepatitis E virus (HEV) strains within the species Orthohepevirus A in
the family Hepeviridae are zoonotic. Recently, a genotype 4 HEV was reportedly detected in …

A safe and effective vaccine against COVID-19 is urgently needed in quantities sufficient to
immunise large populations. We report the preclinical development of two BNT162b vaccine …

Multivalent O-antigen polysaccharide glycoconjugate vaccines are under development to
prevent invasive infections caused by pathogenic Enterobacteriaceae. Sequence type 131 (…

Objective To investigate the serum and synovial fluid serum amyloid A (SAA) response in
equine models of synovitis and septic arthritis and to compare handheld and validated …