Intra-cellular active transport by native cargos is ubiquitous. We investigate the motion of
spherical nano-particles (NPs) grafted with flexible polymers that end with a nuclear localization …

Motor proteins are biological machines that convert chemical energy stored in ATP to mechanical
work. Kinesin and dynein are microtubule (MT)-associated motor proteins that, among …

Targeting the cell nucleus remains a challenge for drug delivery. Here, we present a universal
platform for the smart design of nanoparticle (NP) decoration that is based on: (i) a spacer …

As a seminal tool in self-supervised representation learning, contrastive learning has gained
unprecedented attention in recent years. In essence, contrastive learning aims to leverage …

Background Dynein is a cytoskeletal molecular motor protein that transports cellular cargoes
along microtubules. Biomimetic synthetic peptides designed to bind dynein have been …

Native cargos achieve efficient intra-cellular active transport by recruiting multiple motors
proteins from the cytoplasm. Here we investigate the motion of spherical nano-particles (NPs) – …

Laboratory experiments searching for galactic dark matter particles scattering off nuclei have
so far not been able to establish a discovery. We use data from the XENON100 experiment …

Breakthroughs in science, technology, engineering and math (STEM) change the way we
live our lives. While these breakthroughs can find the cure for the most lethal diseases, every …

Neurodegenerative diseases gradually degrade neurons, often without noticeable symptoms
for decades. The impairment of the cytoskeleton in neurites (ie, axons and dendrites), …

Steady-state and time-resolved emission techniques were used to study the photoprotolytic
properties of three recently synthesized strong quinone cyanine photoacids (QCy7 and its …