User profiles for Ivan Skelin

Ivan Skelin

Neuron2Brain Lab, Krembil Research Institute - University Health Network, University of …
Verified email at uhn.ca
Cited by 1040

[HTML][HTML] Gender bias in academia: A lifetime problem that needs solutions

…, A Perry, P Pinheiro-Chagas, SK Riès, I Saez, I Skelin… - Neuron, 2021 - cell.com
Despite increased awareness of the lack of gender equity in academia and a growing
number of initiatives to address issues of diversity, change is slow, and inequalities remain. A …

[HTML][HTML] A consensus statement on detection of hippocampal sharp wave ripples and differentiation from other fast oscillations

…, JW Rueckemann, JJ Sakon, I Skelin… - Nature …, 2022 - nature.com
Decades of rodent research have established the role of hippocampal sharp wave ripples (SPW-Rs)
in consolidating and guiding experience. More recently, intracranial recordings in …

Hippocampal coupling with cortical and subcortical structures in the context of memory consolidation

I Skelin, S Kilianski, BL McNaughton - Neurobiology of learning and …, 2019 - Elsevier
Memory consolidation is a gradual process through which episodic memories become
incorporated into long-term 'semantic' representations. It likely involves reactivation of neural …

Coupling between slow waves and sharp-wave ripples engages distributed neural activity during sleep in humans

I Skelin, H Zhang, J Zheng, S Ma… - Proceedings of the …, 2021 - National Acad Sciences
Hippocampal-dependent memory consolidation during sleep is hypothesized to depend on
the synchronization of distributed neuronal ensembles, organized by the hippocampal sharp-…

[PDF][PDF] Laminar organization of encoding and memory reactivation in the parietal cortex

AA Wilber, I Skelin, W Wu, BL McNaughton - Neuron, 2017 - cell.com
Egocentric neural coding has been observed in parietal cortex (PC), but its topographical
and laminar organization is not well characterized. We used multi-site recording to look for …

[PDF][PDF] Impaired hippocampal-cortical interactions during sleep in a mouse model of Alzheimer's disease

SD Cushing, I Skelin, SC Moseley, AC Stimmell… - Current Biology, 2020 - cell.com
Spatial learning is impaired in humans with preclinical Alzheimer's disease (AD). We
reported similar impairments in 3xTg-AD mice learning a spatial reorientation task. Memory …

[HTML][HTML] Acute NMDA receptor antagonism disrupts synchronization of action potential firing in rat prefrontal cortex

LA Molina, I Skelin, AJ Gruber - PloS one, 2014 - journals.plos.org
Antagonists of N-methyl-D-aspartate receptors (NMDAR) have psychotomimetic effects in
humans and are used to model schizophrenia in animals. We used high-density …

Imaging in Vivo Glutamate Fluctuations with [11C]ABP688: A GLT-1 Challenge with Ceftriaxone

…, ES Schirrmacher, JP Soucy, I Skelin… - Journal of Cerebral …, 2015 - journals.sagepub.com
Molecular imaging offers unprecedented opportunities for investigating dynamic changes
underlying neuropsychiatric conditions. Here, we evaluated whether [ 11 C]ABP688, a positron …

Lesions of dorsal striatum eliminate lose‐switch responding but not mixed‐response strategies in rats

I Skelin, R Hakstol, J VanOyen… - European Journal of …, 2014 - Wiley Online Library
We used focal brain lesions in rats to examine how dorsomedial ( DMS ) and dorsolateral (
DLS ) regions of the striatum differently contribute to response adaptation driven by the …

Gender differences in α-[11C] MTrp brain trapping, an index of serotonin synthesis, in medication-free individuals with major depressive disorder: A positron emission …

BN Frey, I Skelin, Y Sakai, M Nishikawa… - Psychiatry Research …, 2010 - Elsevier
Women are at higher risk than men for developing major depressive disorder (MDD), but
the mechanisms underlying this higher risk are unknown. Here, we report proportionally …