Robust heat shock induces eIF2α-phosphorylation-independent assembly of stress granules containing eIF3 and 40S ribosomal subunits in budding yeast …
T Grousl, P Ivanov, I Frydlová, P Vasicová… - Journal of cell …, 2009 - journals.biologists.com
Environmental stresses inducing translation arrest are accompanied by the deposition of
translational components into stress granules (SGs) serving as mRNA triage sites. It has …
translational components into stress granules (SGs) serving as mRNA triage sites. It has …
[HTML][HTML] Heat Shock-Induced Accumulation of Translation Elongation and Termination Factors Precedes Assembly of Stress Granules in S. cerevisiae
In response to severe environmental stresses eukaryotic cells shut down translation and
accumulate components of the translational machinery in stress granules (SGs). Since they …
accumulate components of the translational machinery in stress granules (SGs). Since they …
[HTML][HTML] Cytotoxicity of the effector protein BteA was attenuated in Bordetella pertussis by insertion of an alanine residue
J Bayram, I Malcova, L Sinkovec, J Holubova… - PLoS …, 2020 - journals.plos.org
Bordetella bronchiseptica and Bordetella pertussis are closely related respiratory
pathogens that evolved from a common bacterial ancestor. While B. bronchiseptica has an …
pathogens that evolved from a common bacterial ancestor. While B. bronchiseptica has an …
BopN is a Gatekeeper of the Bordetella Type III Secretion System
…, L Bumba, T Prudnikova, I Malcova… - Microbiology …, 2023 - Am Soc Microbiol
The classical Bordetella species infect the respiratory tract of mammals. While B. bronchiseptica
causes rather chronic respiratory infections in a variety of mammals, the human-adapted …
causes rather chronic respiratory infections in a variety of mammals, the human-adapted …
New integrative modules for multicolor-protein labeling and live-cell imaging in Saccharomyces cerevisiae
I Malcova, M Farkasovsky, L Senohrabkova… - FEMS Yeast …, 2016 - academic.oup.com
Live-imaging analysis is performed in many laboratories all over the world. Various tools
have been developed to enable protein labeling either in plasmid or genomic context in live …
have been developed to enable protein labeling either in plasmid or genomic context in live …
The Stationary-Phase Cells of Saccharomyces cerevisiae Display Dynamic Actin Filaments Required for Processes Extending Chronological Life Span
P Vasicova, R Lejskova, I Malcova… - Molecular and cellular …, 2015 - Taylor & Francis
Stationary-growth-phase Saccharomyces cerevisiae yeast cultures consist of nondividing
cells that undergo chronological aging. For their successful survival, the turnover of proteins …
cells that undergo chronological aging. For their successful survival, the turnover of proteins …
[HTML][HTML] eIF3a destabilization and TDP-43 alter dynamics of heat-induced stress granules
I Malcova, L Senohrabkova, L Novakova… - International Journal of …, 2021 - mdpi.com
Stress granules (SGs) are membrane-less assemblies arising upon various stresses in
eukaryotic cells. They sequester mRNAs and proteins from stressful conditions and modulate …
eukaryotic cells. They sequester mRNAs and proteins from stressful conditions and modulate …
Vps factors are required for efficient transcription elongation in budding yeast
There is increasing evidence that certain Vacuolar protein sorting (Vps) proteins, factors that
mediate vesicular protein trafficking, have additional roles in regulating transcription factors …
mediate vesicular protein trafficking, have additional roles in regulating transcription factors …
[HTML][HTML] Lipid binding by the N-terminal motif mediates plasma membrane localization of Bordetella effector protein BteA
I Malcova, L Bumba, F Uljanic, D Kuzmenko… - Journal of Biological …, 2021 - ASBMB
The respiratory pathogens Bordetella pertussis and Bordetella bronchiseptica employ a
type III secretion system (T3SS) to inject a 69-kDa BteA effector protein into host cells. This …
type III secretion system (T3SS) to inject a 69-kDa BteA effector protein into host cells. This …
Deregulation of DSE1 Gene Expression Results in Aberrant Budding within the Birth Scar and Cell Wall Integrity Pathway Activation in Saccharomyces cerevisiae
I Frýdlová, I Malcová, P Vašicová, J Hašek - Eukaryotic Cell, 2009 - Am Soc Microbiol
Strains of Saccharomyces cerevisiae lacking Isw2, the catalytic subunit of the Isw2 chromatin
remodeling complex, show the mating type-independent activation of the cell wall integrity (…
remodeling complex, show the mating type-independent activation of the cell wall integrity (…