Stem cells present unique regenerative abilities, offering great potential for treatment of
prevalent pathologies such as diabetes, neurodegenerative and heart diseases. Various …

The Gram-negative bacterium Azotobacter vinelandii can synthetize the biopolymer alginate
that has material properties appropriate for plenty of applications in industry as well as in …

The transcriptional regulator CITED2 is essential for heart development. Here, we investigated
the role of CITED2 in the specification of cardiac cell fate from mouse embryonic stem …

Alginate production and gene expression of genes involved in alginate biosynthesis were
evaluated in continuous cultures under dissolved oxygen tension (DOT) controlled conditions. …

CITED2 is a ubiquitously expressed nuclear protein exhibiting a high affinity for the cysteine–histidine–rich
domain 1 (CH1) of the transcriptional co-activators CBP/p300. CITED2 is …

Identifying novel players of the pluripotency gene regulatory network centered on Oct4, Sox2,
and Nanog as well as delineating the interactions within the complex network is key to …

P-selectin glycoprotein ligand-1 (PSGL-1) is a membrane-bound glycoprotein expressed in
lymphoid and myeloid cells. It is a ligand of P-, E- and L-selectin and is involved in T cell …

T-cell acute lymphoblastic leukemia (T-ALL) and T-lymphoblastic lymphomas (T-LBL) are
aggressive malignancies of thymocytes. The role of thymic microenvironmental cells and …

CDKN2A deletion is the most frequent genetic alteration in T-cell acute lymphoblastic
leukemia (T-ALL), occurring across all molecular and immunophenotypic subtypes. CDKN2A …

The pre-T cell receptor (TCR) and TCR complexes are frequently expressed in T-cell acute
lymphoblastic leukemia (T-ALL), an aggressive T cell precursor malignancy. Although …