… Drafting of the manuscript: Apostolova and Dinov. Critical revision of the manuscript for …
, and an anonymous donor (Drs Apostolova and Dinov). The study was also supported by the …

Motivation: Integrative mathematical and statistical models of cardiac anatomy and
physiology can play a vital role in understanding cardiac disease phenotype and planning …

Alzheimer's disease is the most common neurodegenerative disorder in the elderly. Amnestic
mild cognitive impairment (MCI) is a relatively newly defined clinical entity that requires …

Sex differences in age- and puberty-related maturation of human brain structure have been
observed in typically developing age-matched boys and girls. Because girls mature 1–2 …

A recently identified variant within the fat mass and obesity-associated (FTO) gene is carried
by 46% of Western Europeans and is associated with an ~1.2 kg higher weight, on average, …

Obesity is associated with lower brain volumes in cognitively normal elderly subjects, but no
study has yet investigated the effects of obesity on brain structure in patients with mild …

The hippocampus is involved at the onset of the neuropathological pathways leading to
Alzheimer's disease (AD). Individuals with mild cognitive impairment (MCI) are at increased risk …

Diffusion imaging tractography is a valuable tool for neuroscience researchers because it
allows the generation of individualized virtual dissections of major white matter tracts in the …

Stroke causes loss of neurological function. Recovery after stroke is facilitated by forced use
of the affected limb and is associated with sprouting of new connections, a process that is …

In this paper, a hybrid discriminative/generative model for brain anatomical structure segmentation
is proposed. The learning aspect of the approach is emphasized. In the discriminative …