User profiles for J Pensar

Johan Pensar

Associate Professor, Statistics and Data Science, University of Oslo
Verified email at math.uio.no
Cited by 1094

[HTML][HTML] Causal discovery for the microbiome

J Corander, WP Hanage, J Pensar - The Lancet Microbe, 2022 - thelancet.com
Measurement and manipulation of the microbiome is generally considered to have great
potential for understanding the causes of complex diseases in humans, developing new …

[HTML][HTML] Genome evolution and the emergence of pathogenicity in avian Escherichia coli

L Mageiros, G Méric, SC Bayliss, J Pensar… - Nature …, 2021 - nature.com
Chickens are the most common birds on Earth and colibacillosis is among the most common
diseases affecting them. This major threat to animal welfare and safe sustainable food …

[HTML][HTML] Disease-associated genotypes of the commensal skin bacterium Staphylococcus epidermidis

G Méric, L Mageiros, J Pensar, M Laabei… - Nature …, 2018 - nature.com
Some of the most common infectious diseases are caused by bacteria that naturally
colonise humans asymptomatically. Combating these opportunistic pathogens requires an …

Plasmids shaped the recent emergence of the major nosocomial pathogen Enterococcus faecium

…, J Top, A McNally, S Puranen, M Pesonen, J Pensar… - MBio, 2020 - Am Soc Microbiol
Enterococcus faecium is a gut commensal of humans and animals but is also listed on the
WHO global priority list of multidrug-resistant pathogens. Many of its antibiotic resistance traits …

The immuneML ecosystem for machine learning analysis of adaptive immune receptor repertoires

…, A Martini, T Minotto, J Pensar… - Nature Machine …, 2021 - nature.com
Adaptive immune receptor repertoires (AIRR) are key targets for biomedical research as they
record past and ongoing adaptive immune responses. The capacity of machine learning (…

Improving generalization of machine learning-identified biomarkers using causal modelling with examples from immune receptor diagnostics

M Pavlović, GS Al Hajj, C Kanduri, J Pensar… - Nature Machine …, 2024 - nature.com
Abstract Machine learning is increasingly used to discover diagnostic and prognostic
biomarkers from high-dimensional molecular data. However, a variety of factors related to …

The genetics of sexuality and aggression (GSA) twin samples in Finland

…, H Nyman, J Pensar, J Corander… - Twin Research and …, 2013 - cambridge.org
… Retrieved from http://pxweb2.stat.fi/Dialog/ varval.asp?ma=030 vkour tau 103 fi&ti=Perusasteen+j%
E4lkeisi%E4+tutkintoja+suorittanut+v%E4est%F6+ koulutusasteen%2C+maakunnan…

Integrated analysis of population genomics, transcriptomics and virulence provides novel insights into Streptococcus pyogenes pathogenesis

…, J Pensar, ER Davenport, AG Clark, J Corander… - Nature …, 2019 - nature.com
Streptococcus pyogenes causes 700 million human infections annually worldwide, yet, despite
a century of intensive effort, there is no licensed vaccine against this bacterium. Although …

Towards scalable bayesian learning of causal dags

J Viinikka, A Hyttinen, J Pensar… - Advances in Neural …, 2020 - proceedings.neurips.cc
… From G alone, we can read off whether a node j is an ancestor of i, and thus xj potentially …
by summing up the weights of all directed paths from j to i, the weight of a path equalling the …

House price prediction with gradient boosted trees under different loss functions

A Hjort, J Pensar, I Scheel… - Journal of property …, 2022 - Taylor & Francis
… that partition the feature space into J disjoint subsets I 1 , … , I J . The subsets are found by
… on the decision tree, and each leaf j is equipped with a constant value w ( j ) that serves as a …