Mitochondria are highly dynamic organelles undergoing coordinated cycles of fission and
fusion, referred as ‘mitochondrial dynamics’, in order to maintain their shape, distribution and …

… However, one study showed that MICU1-KO in C57BL/6 J background was lethal a few
hours after birth due to failure in basic vital functions [61], whereas the other obtained a high …

The existence of the bcl-2 (B-cell lymphoma-2) gene was reported nearly 30years ago. Yet,
Bcl-2 family group of proteins still surprises us with their structural and functional diversity. …

Flap endonucleases (FENs) isolated from archaea are shown to recognize and cleave a
structure formed when two overlapping oligonucleotides hybridize to a target DNA strand. The …

… j,k, Immunoblots of specified proteins (j) and Ifnb1 mRNA expression measured by qRT–PCR
(k) in cFh1 fl/fl cells transfected with the indicated siRNAs and treated with MMF for the …

The mechanisms that link environmental and intracellular stimuli to mitochondrial functions,
including fission/fusion, ATP production, metabolite biogenesis, and apoptosis, are not well …

Peroxisomes function together with mitochondria in a number of essential biochemical pathways,
from bile acid synthesis to fatty acid oxidation 1 . Peroxisomes grow and divide from pre…

There has been evidence that mitochondrial fragmentation is required for apoptosis, but the
molecular links between the machinery regulating dynamics and cell death have been …

The invasive signal amplification reaction has been previously developed for quantitative
detection of nucleic acids and discrimination of single-nucleotide polymorphisms. Here we …

Human respiratory viruses are a diverse group of pathogens composed of hundreds of virus
strains, and this presents a major challenge for diagnostic laboratories. To efficiently detect …