Computational programs for predicting RNA sequences with desired folding properties have
been extensively developed and expanded in the past several years. Given a secondary …

Motivation: Proteins of all kinds can self-assemble into highly ordered β-sheet aggregates
known as amyloid fibrils, important both biologically and clinically. However, the specific …

Since the development of the first docking program in 1982, the use of docking-based in silico
screening for potentially bioactive molecule discovery has become a common strategy in …

To the Editor—Over the past decade, online science discovery games (SDGs) have become
an increasingly popular practice for engaging the public in research activities. This …

The wealth of the combinatorics of nucleotide base pairs enables RNA molecules to
assemble into sophisticated interaction networks, which are used to create complex 3D …

Motivation: The prediction of RNA 3D structures from its sequence only is a milestone to RNA
function analysis and prediction. In recent years, many methods addressed this challenge, …

Motivations: The design of RNA sequences folding into predefined secondary structures is a
milestone for many synthetic biology and gene therapy studies. Most of the current software …

With nearly three billion players, video games are more popular than ever. Casual puzzle
games are among the most played categories. These games capitalize on the players’ …

RNA-small molecule binding is a key regulatory mechanism which can stabilize 3D structures
and activate molecular functions. The discovery of RNA-targeting compounds is thus a …

Serious scientific games are games whose purpose is not just fun. In the field of science, the
serious goals include crucial activities for scientists: outreach, teaching and research. The …