In this work, we study the diversity of bathypelagic microbial eukaryotes (0.8–20 μm) in the
global ocean. Seawater samples from 3000 to 4000 m depth from 27 stations in the Atlantic, …

Background Contemporary deep learning approaches show cutting-edge performance in a
variety of complex prediction tasks. Nonetheless, the application of deep learning in …

Detailed genetic analyses of HGT1 bladder tumors identify features that correlate with outcome,
eg, high mutational burden, ERCC2 mutations, and high APOBEC-A/ERCC2 mutation …

Background A comprehensive understanding of cancer has been furthered with technological
improvements and decreasing costs of next-generation sequencing (NGS). However, the …

Immune checkpoint inhibitors (ICI) have revolutionized cancer treatment and can result in
complete remissions even at advanced stages of the disease. However, only a small fraction of …

Mutations and activation of the PI3K signaling pathway in breast cancer cells have been
linked to brain metastases. However, here we describe that in some breast cancer brain …

One of the hallmarks of SARS-CoV-2 infection is an induced immune dysregulation, in
some cases resulting in cytokine storm syndrome and acute respiratory distress syndrome (ARDS)…

The clinical manifestations of SARS-CoV-2 infection vary widely, from asymptomatic infection
to the development of acute respiratory distress syndrome (ARDS) and death. The host …

The impact of tumor focality on prostate cancer (PCa) prognosis has been addressed in
several studies with conflicting results. Tumor foci from multifocal (MF) PCa can show highly …

Introduction Neoadjuvant and adjuvant immune checkpoint blockade (ICB) have recently
become standard of care in resectable non-small cell lung cancer (NSCLC). Yet, biomarkers …