The primary structure of the Escherichia coli rrnB ribosomal RNA operon has been determined.
The sequence contains the genes for 16 S, 23 S and 5 S ribosomal RNAs, the secondary …

T> HE QUESTION OF WHY MAMMALIAN GENOMES ARE" BUR-dened" with a large number
of nonfunctional genes has puzzled molecular and evolutionary biologists. These genes …

A plasmid cloning vector system has been constructed that allows for the production of large
quantities of foreign proteins or fragments thereof, in an unfused state. These vectors …

There is growing evidence that mammalian genomes produce thousands of transcripts that
do not encode proteins, and this RNA class might even rival the complexity of mRNAs. There …

A strong promoter has been cloned on a series of plasmid vectors that facilitate the
expression of cloned genes. This promoter, named tac [first described by DeBoer et al. (inRodriguez, …

The multitude of G-protein coupled receptor (GPR) superfamily cDNAs recently isolated has
exceeded the number of receptor subtypes anticipated by pharmacological studies. Analysis …

We have identified three C/D-box small nucleolar RNAs (snoRNAs) and one H/ACA-box
snoRNA in mouse and human. In mice, all four snoRNAs (MBII-13, MBII-52, MBII-85, and MBI-36…

In a specialized cDNA library from the archaeon Archaeoglobus fulgidus we have identified
a total of 86 different expressed RNA sequences potentially encoding previously …

A secondary structure model for 23S ribosomal RNA has been constructed on the basis of
comparative sequence data, including the complete sequences from E. coli. Bacillus …

In mouse brain cDNA libraries generated from small RNA molecules we have identified a
total of 201 different expressed RNA sequences potentially encoding novel small non‐…