Modular analysis of the transcriptional regulatory network of E. coli

O Resendis-Antonio, JA Freyre-Gonzalez… - TRENDS in …, 2005 - cell.com
The transcriptional network of Escherichia coli is currently the best-understood regulatory
network of a single cell. Motivated by statistical evidence, suggesting a hierarchical modular …

[HTML][HTML] Identification of regulatory network topological units coordinating the genome-wide transcriptional response to glucose in Escherichia coli

RM Gutierrez-Ríos, JA Freyre-Gonzalez, O Resendis… - BMC microbiology, 2007 - Springer
Background Glucose is the preferred carbon and energy source for Escherichia coli. A
complex regulatory network coordinates gene expression, transport and enzyme activities in …

[HTML][HTML] Functional architecture of Escherichia coli: new insights provided by a natural decomposition approach

JA Freyre-González, JA Alonso-Pavón… - Genome biology, 2008 - Springer
Background Previous studies have used different methods in an effort to extract the modular
organization of transcriptional regulatory networks. However, these approaches are not …

Calcitriol increases Dicer expression and modifies the microRNAs signature in SiHa cervical cancer cells

…, L Díaz, V Ortíz, JA Freyre-González… - … and cell biology, 2015 - cdnsciencepub.com
MicroRNAs play important roles in cancer biology. Calcitriol, the hormonal form of vitamin D
3 , regulates microRNAs expression in tumor cells. In the present study we asked if calcitriol …

[HTML][HTML] Abasy Atlas v2. 2: The most comprehensive and up-to-date inventory of meta-curated, historical, bacterial regulatory networks, their completeness and system …

…, A Tauch, JA Freyre-González - Computational and …, 2020 - Elsevier
Some organism-specific databases about regulation in bacteria have become larger, accelerated
by high-throughput methodologies, while others are no longer updated or accessible. …

[HTML][HTML] Improving gene regulatory network inference and assessment: The importance of using network structure

…, MA Tello-Palencia, JA Freyre-González - Frontiers in …, 2023 - frontiersin.org
Gene regulatory networks are graph models representing cellular transcription events. Networks
are far from complete due to time and resource consumption for experimental validation …

[HTML][HTML] Lessons from the modular organization of the transcriptional regulatory network of Bacillus subtilis

JA Freyre-González, AM Manjarrez-Casas… - BMC systems …, 2013 - Springer
Background The regulation of gene expression at the transcriptional level is a fundamental
process in prokaryotes. Among the different kind of mechanisms modulating gene …

Abasy Atlas: a comprehensive inventory of systems, global network properties and systems-level elements across bacteria

…, A Tauch, JA Freyre-González - Database, 2016 - academic.oup.com
The availability of databases electronically encoding curated regulatory networks and of
high-throughput technologies and methods to discover regulatory interactions provides an …

Functional architecture and global properties of the Corynebacterium glutamicum regulatory network: Novel insights from a dataset with a high genomic coverage

JA Freyre-González, A Tauch - Journal of biotechnology, 2017 - Elsevier
Corynebacterium glutamicum is a Gram-positive, anaerobic, rod-shaped soil bacterium able
to grow on a diversity of carbon sources like sugars and organic acids. It is a …

[HTML][HTML] Rhizobium etli CFN42 proteomes showed isoenzymes in free-living and symbiosis with a different transcriptional regulation inferred from a transcriptional …

…, JM Escorcia-Rodríguez, JA Freyre-González… - Frontiers in …, 2022 - frontiersin.org
A comparative proteomic study at 6 h of growth in minimal medium (MM) and bacteroids at
18 days of symbiosis of Rhizobium etli CFN42 with the Phaseolus vulgaris leguminous plant …