User profiles for J. B. de la Serna

Jorge Bernardino de la Serna

Senior Lecturer, Imperial College London, National Heart and Lung Institute
Verified email at imperial.ac.uk
Cited by 2994

[HTML][HTML] Cholesterol rules: direct observation of the coexistence of two fluid phases in native pulmonary surfactant membranes at physiological temperatures

JB de la Serna, J Perez-Gil, AC Simonsen… - Journal of Biological …, 2004 - ASBMB
… Jorge Bernardino de la Serna Jorge Bernardino de la Serna … Giant unilamellar (A–C) and
multilamellar (D) vesicles formed from native pulmonary surfactant material. A, transmission …

[HTML][HTML] Inactivation of pulmonary surfactant due to serum-inhibited adsorption and reversal by hydrophilic polymers: experimental

HW Taeusch, JB De La Serna, J Perez-Gil, C Alonso… - Biophysical journal, 2005 - cell.com
… Jorge Bernardino de la Serna Jorge Bernardino de la Serna … four lung surfactant specific
proteins (SP-A, B, C, and D) that line the interior of the lung alveoli. Lung surfactant lowers the …

Cytoskeletal actin dynamics shape a ramifying actin network underpinning immunological synapse formation

…, I Pedroza-Pacheco, D Waithe, JB de la Serna… - Science …, 2017 - science.org
T cell activation and especially trafficking of T cell receptor microclusters during immunological
synapse formation are widely thought to rely on cytoskeletal remodeling. However, …

Recent advances in alveolar biology: some new looks at the alveolar interface

…, T Haller, NO Petersen, YY Zuo, JB de la Serna… - Respiratory physiology …, 2010 - Elsevier
… Interestingly, Bernardino de la Serna and Bagatolli found SP-D KO surfactant possessed a
slightly higher disaturated PL content, but similar overall surface tension characteristics on a …

Filaggrin inhibits generation of CD1a neolipid antigens by house dust mite–derived phospholipase

…, D Gutowska-Owsiak, JB de la Serna… - Science translational …, 2016 - science.org
Atopic dermatitis is a common pruritic skin disease in which barrier dysfunction and
cutaneous inflammation contribute to pathogenesis. Mechanisms underlying the associated …

[PDF][PDF] Segregated phases in pulmonary surfactant membranes do not show coexistence of lipid populations with differentiated dynamic properties

JB de La Serna, G Orädd, LA Bagatolli, AC Simonsen… - Biophysical journal, 2009 - cell.com
… paper is dedicated to the memory of Maria Luisa de la Serna. … Jorge Bernardino de la
Serna’s present address is MEMPHYS-… coefficients obtained did not depend on the value of D. …

Capturing resting T cells: the perils of PLL

…, M Fritzsche, RA Fernandes, JB de la Serna… - Nature …, 2018 - nature.com
To the editor—Full understanding of lymphocyte activation will require thorough characterization
of the ‘resting’state and how it changes. Surfaces coated with the cationic homopolymer …

[PDF][PDF] Inhibition of pulmonary surfactant adsorption by serum and the mechanisms of reversal by hydrophilic polymers: theory

JA Zasadzinski, TF Alig, C Alonso, JB De La Serna… - Biophysical journal, 2005 - cell.com
A theory based on the Smolukowski analysis of colloid stability shows that the presence of
charged, surface-active serum proteins at the alveolar air-liquid interface can severely reduce …

[HTML][HTML] Multiphoton excitation fluorescence microscopy in planar membrane systems

…, JB de la Serna, K Wagner, LA Bagatolli - Biochimica et Biophysica …, 2010 - Elsevier
The feasibility of applying multiphoton excitation fluorescence microscopy-related techniques
in planar membrane systems, such as lipid monolayers at the air–water interface (named …

Using nanoscopy to probe the biological activity of antimicrobial leads that display potent activity against pathogenic, multidrug resistant, gram-negative bacteria

KL Smitten, HM Southam, JB de la Serna, MR Gill… - ACS …, 2019 - ACS Publications
… Jorge Bernardino de la Serna Jorge Bernardino de la Serna … Both deconvoluted
diffraction-limited images (d-LSCM) and super-resolution (d-STED) images were processed using …