Cholestasis, a hallmark feature of hepatobiliary disease, is characterized by the retention of
biliary constituents. Some of these constituents, such as bile acids, inflict damage to …

Prehabilitation improves surgical outcomes in patients undergoing surgery. However, patients
preparing for orthotopic liver transplantation (OLT) are physically “frail” and suffer from …

… This work was supported by funding from the Austrian Science Fund (FWF) project ‘Transmembrane
Transporters in Health and Disease’ (F3517; to Michael Trauner), and by an EASL Dame …

Organ transplantation is a life-saving treatment for patients with end-stage disease, but survival
rates after transplantation vary considerably. There is now increasing evidence that the …

Background & Aims Hepatocellular adenomas (HCA) are rare, hormone‐driven, benign
liver tumours. HCA >50 mm are associated with haemorrhage and malignant transformation. …

BACKGROUND & AIMS: We tested the hypothesis that oral administration of bile salts, which
are known to increase the biliary excretion of unconjugated bilirubin (UCB), decreases …

Objective Benign liver tumours (BLT) are increasingly diagnosed as incidentalomas. Clinical
implications and management vary across and within the different types of BLT. High-…

Background Hepatocellular adenomas (HCA) are benign liver tumors at risk of hemorrhage.
The influence of pregnancy on HCA growth and potential bleeding remains unclear. This …

BACKGROUND & AIMS: Severe unconjugated hyperbilirubinemia, as occurs in Crigler–Najjar
disease and neonatal jaundice, carries the risk of neurotoxicity. This neurotoxicity is …

Background and aims Several conditions that delay gastrointestinal transit are associated
with unconjugated hyperbilirubinaemia. We hypothesised that the gastrointestinal transit time …