Introduction What is the current status of photodynamic therapy (PDT) with regard to treating
malignant brain tumors? Despite several decades of effort, PDT has yet to achieve standard …

Vitamin C is a wide spectrum antioxidant essential for humans, which are unable to synthesize
the vitamin and must obtain it from dietary sources. There are two biologically important …

The acute chest syndrome (ACS), a pneumonia-like illness in sickle cell patients, is one of
the most frequent causes of their morbidity and hospitalizations. Repeated ACS events may …

… JC Vera and CW Wheat contributed equally to this work. … JC Vera and CW Wheat
contributed equally to this work. … JC Vera and CW Wheat contributed equally to this work. …

ALTHOUGH vitamin C is critical to human physiology 1–5 , it is not clear how it is taken up
into cells. The kinetics of cell and tissue accumulation of ascorbic acid in vitro indicate that the …

Vitamin C concentrations in the brain exceed those in blood by 10-fold. In both tissues, the
vitamin is present primarily in the reduced form, ascorbic acid. We identified the chemical form …

… Juan Carlos Vera … Juan Carlos Vera … We have previously demonstrated that the human
myeloid HL-60 cells express only GLUT1 (Vera et al., 1995, Nualart et al., 2003), thus, these cells …

The transport of pyruvate and lactate across cellular membranes is an essential process in
mammalian cells and is mediated by the H + /monocarboxylate transporters (MCTs). We have …

The primary metabolic characteristic of malignant cells is an increased uptake of glucose
and its anaerobic metabolism. We studied the expression and function of the glucose …

… Spielholz C., Golde DW, Houghton AN, Nualart F., Vera JC Increased facilitated transport
of dehydroascorbic acid without changes in sodium-dependent ascorbate transport in human …