… Author links open overlay panel Eunho Suh 1 , Jonathan D Bohbot 2 , Laurence J
Zwiebel 1 … JD Bohbot, JC Dickens … JD Bohbot, JC Dickens …

The mode of action of mosquito repellents remains a controversial topic. However,
electrophysiological studies and molecular approaches have provided a better understanding of how …

The olfactory receptor neurons of insects and vertebrates are gated by odorant receptor (OR)
proteins of which several members have been shown to exhibit remarkable sensitivity and …

Anopheles gambiae is the principal Afrotropical vector for human malaria, in which olfaction
mediates a wide range of both adult and larval behaviors. Indeed, mosquitoes depend on …

Background DEET, 2-undecanone (2-U), IR3535 and Picaridin are widely used as insect
repellents to prevent interactions between humans and many arthropods including mosquitoes. …

Several lines of evidence suggest that insect repellent molecules reduce mosquito–host
contacts by interacting with odorants and odorant receptors (ORs), thereby ultimately affecting …

Enantiomers differ only in the left or right handedness (chirality) of their orientations and
exhibit identical chemical and physical properties. In chemical communication systems, …

Aedes aegypti and Anopheles gambiae are among the best-characterized mosquito species
within the Culicinae and Anophelinae mosquito clades which diverged ∼150 million years …

The modulation of insect behavior for the purpose of controlling the spread of infectious
diseases has been the task of a few insect repellents for which the mechanistic modes of action …

The molecular basis of odorant detection and its corollary, the task of the odorant receptor,
are fundamental to understanding olfactory coding and sensory ecology. Based on their …