Symptoms and functional status of patients with atrial fibrillation: state of the art and future research opportunities
Atrial fibrillation (AF) is the most common arrhythmia and is associated with increased risks
of stroke, heart failure, dementia, and death. 1–8 Because the number of elderly individuals …
of stroke, heart failure, dementia, and death. 1–8 Because the number of elderly individuals …
Neuronal gap junctions: making and breaking connections during development and injury
AB Belousov, JD Fontes - Trends in neurosciences, 2013 - cell.com
In the mammalian central nervous system (CNS), coupling of neurons by gap junctions (ie,
electrical synapses) and the expression of the neuronal gap junction protein, connexin 36 (…
electrical synapses) and the expression of the neuronal gap junction protein, connexin 36 (…
[HTML][HTML] Gap junctions and hemichannels: communicating cell death in neurodevelopment and disease
AB Belousov, JD Fontes, M Freitas-Andrade, CC Naus - BMC cell biology, 2017 - Springer
Gap junctions are unique membrane channels that play a significant role in intercellular
communication in the developing and mature central nervous system (CNS). These channels …
communication in the developing and mature central nervous system (CNS). These channels …
Simple risk model predicts incidence of atrial fibrillation in a racially and geographically diverse population: the CHARGE‐AF consortium
Background Tools for the prediction of atrial fibrillation ( AF ) may identify high‐risk individuals
more likely to benefit from preventive interventions and serve as a benchmark to test novel …
more likely to benefit from preventive interventions and serve as a benchmark to test novel …
Meta-analysis of genome-wide association studies in> 80 000 subjects identifies multiple loci for C-reactive protein levels
Background— C-reactive protein (CRP) is a heritable marker of chronic inflammation that is
strongly associated with cardiovascular disease. We sought to identify genetic variants that …
strongly associated with cardiovascular disease. We sought to identify genetic variants that …
Association between familial atrial fibrillation and risk of new-onset atrial fibrillation
Context Although the heritability of atrial fibrillation (AF) is established, the contribution of
familial AF to predicting new-onset AF remains unknown. Objective To determine whether …
familial AF to predicting new-onset AF remains unknown. Objective To determine whether …
Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes.
CH Chang, JD Fontes, M Peterlin… - The Journal of …, 1994 - rupress.org
The class II transactivator (CIITA) has been shown to be required for major histocompatibility
complex (MHC) class II gene expression in B cells and its deficiency is responsible for a …
complex (MHC) class II gene expression in B cells and its deficiency is responsible for a …
B-type natriuretic peptide and C-reactive protein in the prediction of atrial fibrillation risk: the CHARGE-AF Consortium of community-based cohort studies
Aims B-type natriuretic peptide (BNP) and C-reactive protein (CRP) predict atrial fibrillation (AF)
risk. However, their risk stratification abilities in the broad community remain uncertain. …
risk. However, their risk stratification abilities in the broad community remain uncertain. …
Outcomes of Medicare beneficiaries undergoing catheter ablation for atrial fibrillation
Background— Atrial fibrillation is common among older persons. Catheter ablation is
increasingly used in patients for whom medical therapy has failed. Methods and Results— We …
increasingly used in patients for whom medical therapy has failed. Methods and Results— We …
Risk assessment for incident heart failure in individuals with atrial fibrillation
Background Atrial fibrillation (AF) is a strong risk factor for heart failure (HF); HF onset in patients
with AF is associated with increased morbidity and mortality. Risk factors that predict HF …
with AF is associated with increased morbidity and mortality. Risk factors that predict HF …