User profiles for J. D. Whitesell

Jennifer Whitesell

Cajal Neuroscience
Verified email at cajalneuro.com
Cited by 2425

Survey of spiking in the mouse visual system reveals functional hierarchy

…, C Thompson, K Turner, W Wakeman, JD Whitesell… - Nature, 2021 - nature.com
The anatomy of the mammalian visual system, from the retina to the neocortex, is organized
hierarchically 1 . However, direct observation of cellular-level functional interactions across …

Hierarchical organization of cortical and thalamic connectivity

JA Harris, S Mihalas, KE Hirokawa, JD Whitesell… - Nature, 2019 - nature.com
The mammalian cortex is a laminar structure containing many areas and cell types that are
densely interconnected in complex ways, and for which generalizable principles of …

Mitral cells in the olfactory bulb are mainly excited through a multistep signaling path

…, JD Zak, KF Tanaka, JD Whitesell… - Journal of …, 2012 - Soc Neuroscience
Within the olfactory system, information flow from the periphery onto output mitral cells (MCs)
of the olfactory bulb (OB) has been thought to be mediated by direct synaptic inputs from …

[PDF][PDF] Regional, layer, and cell-type-specific connectivity of the mouse default mode network

JD Whitesell, A Liska, L Coletta, KE Hirokawa, P Bohn… - Neuron, 2021 - cell.com
Whitesell et al. use modern neuroanatomical tools in the mouse, including whole-brain
imaging and viral tracing, to provide highresolution anatomical descriptions and identify cell type …

Nontoxic, double-deletion-mutant rabies viral vectors for retrograde targeting of projection neurons

…, A Beyeler, GG Calhoon, G Glober, JD Whitesell… - Nature …, 2018 - nature.com
Recombinant rabies viral vectors have proven useful for applications including retrograde
targeting of projection neurons and monosynaptic tracing, but their cytotoxicity has limited their …

Network structure of the mouse brain connectome with voxel resolution

L Coletta, M Pagani, JD Whitesell, JA Harris… - Science …, 2020 - science.org
Fine-grained descriptions of brain connectivity are required to understand how neural
information is processed and relayed across spatial scales. Previous investigations of the mouse …

Kv2. 1 potassium channels are retained within dynamic cell surface microdomains that are defined by a perimeter fence

KMS O'Connell, AS Rolig, JD Whitesell… - Journal of …, 2006 - Soc Neuroscience
Ion channel localization to specific cell surface regions is essential for proper neuronal
function. The Kv2.1 K + channel forms large clusters on the plasma membrane of hippocampal …

Whole brain imaging reveals distinct spatial patterns of amyloid beta deposition in three mouse models of Alzheimer's disease

JD Whitesell, AR Buckley, JE Knox… - Journal of …, 2019 - Wiley Online Library
A variety of Alzheimer's disease (AD) mouse models overexpress mutant forms of human
amyloid precursor protein (APP), producing high levels of amyloid β (Aβ) and forming plaques. …

High-resolution data-driven model of the mouse connectome

JE Knox, KD Harris, N Graddis, JD Whitesell… - Network …, 2018 - direct.mit.edu
Abstract Knowledge of mesoscopic brain connectivity is important for understanding inter-
and intraregion information processing. Models of structural connectivity are typically …

A survey of spiking activity reveals a functional hierarchy of mouse corticothalamic visual areas

…, C Thompson, K Turner, W Wakeman, JD Whitesell… - Biorxiv, 2019 - biorxiv.org
The mammalian visual system, from retina to neocortex, has been extensively studied at
both anatomical and functional levels. Anatomy indicates the cortico-thalamic system is …