Mesenchymal stem cells (MSC) hold great potential for regenerative medicine because of
their ability for self-renewal and differentiation into tissue-specific cells such as osteoblasts, …

Background: First-generation autologous chondrocyte implantation has limitations, and
introducing new effective cell sources can improve cartilage repair. Purpose: This study was …

Introduction Lateral condyle fractures of the humerus are common paediatric fractures.
However, no conclusive statement has been made about their risk of complications, the …

Regulatable CAR platforms could circumvent toxicities associated with CAR-T therapy, but
existing systems have shortcomings including leakiness and attenuated activity. Here, we …

This study sought to identify critical determinants of mesenchymal stem cell (MSC) potency
using in vitro and in vivo attributes of cells isolated from the bone marrow of age‐ and sex‐…

Bone morphogenetic protein-2 (BMP-2) is a potent osteoinductive factor, yet its clinical use
is limited by a short biological half-life, rapid local clearance and propensity for side effects. …

Bone morphogenetic protein-2 (BMP-2) is known to enhance fracture healing when delivered
via a bovine collagen sponge. However, collagen rapidly releases BMP-2 with a high burst …

A key factor in the tissue engineering approach to tissue repair and regeneration is the use
of appropriate cells. Mesenchymal stem cells (MSCs) are derived from bone marrow stroma …

Bone morphogenetic protein (BMP)-2 is a potent bone healing compound produced at sites
of bone trauma. Here we present a therapeutic strategy to harness the activity of …

Mesenchymal Stem Cells (MSC) are frequently incorporated into osteochondral implants
and cell seeding is often facilitated with hydrogels which exert a profound influence on the …