Alzheimer disease (AD) prevention trials hold the promise to delay or prevent cognitive decline
and dementia onset by intervening before significant neuronal damage occurs. In recent …

Dominantly inherited Alzheimer’s disease (DIAD) causes predictable biological changes
decades before the onset of clinical symptoms, enabling testing of interventions in the …

Background: Due to the high prevalence of Alzheimer's disease (AD) in middle and low-income
countries, there is an urgent need for inexpensive and minimally invasive diagnostic …

Background With no effective treatments for cognitive decline or dementia, improving the
evidence base for modifiable risk factors is a research priority. This study investigated …

Background The World Health Organization (WHO) has reframed health and healthcare for
older people around achieving the goal of healthy ageing. The recent WHO Integrated Care …

Background: Acute stroke treatment is a time-critical process in which every minute counts.
Laboratory biomarkers are needed to aid clinical decisions in the diagnosis. Although …

The recent global severe acute respiratory syndrome coronavirus 2 pandemic will leave its
shadow over mental health in our society, especially among the most vulnerable such as …

INTRODUCTION Population aging translates into more people with chronic non-communicable
diseases, disability, frailty and dependency. The study of frailty-a clinical syndrome …

… Llibre-Guerra MD … Llibre-Guerra MD … Dani J Kim, Jorge J Llibre-Guerra and Matthew
Prina, had full access to all the data in the study and takes responsibility for the integrity and the …

Aging and Alzheimer is a prospective, longitudinal cohort study involving 2944 adults aged
≥65 years from selected areas in Cuba’s Havana and Matanzas Provinces. This door-to-…