User profiles for J. J. Wine
 | Jeffrey WineStanford University Verified email at stanford.edu Cited by 13903 |
[HTML][HTML] The genesis of cystic fibrosis lung disease
JJ Wine - The Journal of clinical investigation, 1999 - Am Soc Clin Investig
James M. Wilson, Editor ductance, and by analogy with the sweat duct (11, 12) this allows
salt levels in the ASL to remain at levels similar to those in plasma. The high salt in the ASL …
salt levels in the ASL to remain at levels similar to those in plasma. The high salt in the ASL …
Submucosal glands and airway defense
JJ Wine, NS Joo - Proceedings of the American Thoracic Society, 2004 - atsjournals.org
… Joo NS, Wu JV, Krouse ME, Saenz Y, Wine JJ. Optical method for quantifying rates of
mucus secretion from single submucosal glands. Am J Physiol Lung Cell Mol Physiol 2001;281:…
mucus secretion from single submucosal glands. Am J Physiol Lung Cell Mol Physiol 2001;281:…
Airway gland structure and function
JH Widdicombe, JJ Wine - Physiological reviews, 2015 - journals.physiology.org
… This has been confirmed in human and pig glands (Wine and Krouse, unpublished data).
7) As discussed further in section VI, immunocytochemistry shows that the transport proteins …
7) As discussed further in section VI, immunocytochemistry shows that the transport proteins …
Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770
…, J Yang, C Young, ER Olson, JJ Wine… - Proceedings of the …, 2009 - National Acad Sciences
Cystic fibrosis (CF) is a fatal genetic disease caused by mutations in the gene encoding the
CF transmembrane conductance regulator (CFTR), a protein kinase A (PKA)-activated …
CF transmembrane conductance regulator (CFTR), a protein kinase A (PKA)-activated …
Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809
Cystic fibrosis (CF) is caused by mutations in the CF transmembrane conductance regulator
(CFTR) gene that impair the function of CFTR, an epithelial chloride channel required for …
(CFTR) gene that impair the function of CFTR, an epithelial chloride channel required for …
[HTML][HTML] Glycerol Reverses the Misfolding Phenotype of the Most Common Cystic Fibrosis Mutation (∗)
The common ΔF508 mutation in the cystic fibrosis transmembrane conductance regulator (CFTR)
interferes with the biosynthetic folding of nascent CFTR polypeptides, leading to their …
interferes with the biosynthetic folding of nascent CFTR polypeptides, leading to their …
Calu-3: a human airway epithelial cell line that shows cAMP-dependent Cl-secretion
Of 12 cell lines derived from human lung cancers, only Calu-3 cells showed high transepithelial
resistance (Rte) and increases in short-circuit current (Isc) in response to mediators. Calu…
resistance (Rte) and increases in short-circuit current (Isc) in response to mediators. Calu…
[HTML][HTML] Disease phenotype of a ferret CFTR-knockout model of cystic fibrosis
Cystic fibrosis (CF) is a recessive disease that affects multiple organs. It is caused by mutations
in CFTR. Animal modeling of this disease has been challenging, with species- and strain-…
in CFTR. Animal modeling of this disease has been challenging, with species- and strain-…
The organization of escape behaviour in the crayfish
JJ Wine, FB Krasne - Journal of Experimental Biology, 1972 - journals.biologists.com
Invertebrate escape reflexes have long been favoured preparations for investigating neuronal
substrates of behaviour. The large size of many of their component neurones make them …
substrates of behaviour. The large size of many of their component neurones make them …
A phase II, double-blind, randomized, placebo-controlled clinical trial of tgAAVCF using maxillary sinus delivery in patients with cystic fibrosis with antrostomies
tgAAVCF, an adeno-associated cystic fibrosis transmembrane conductance regulator (CFTR)
viral vector/gene construct, was administered to 23 patients in a Phase II, double-blind, …
viral vector/gene construct, was administered to 23 patients in a Phase II, double-blind, …