IL-17A was cloned more than 10 years ago and six IL-17 family members (IL-17A-F) have
subsequently been described. IL-17A is largely produced by activated memory T lymphocytes …

T helper 17 (Th17) cells belong to a recently identified T helper subset, in addition to the
traditional Th1 and Th2 subsets. These cells are characterized as preferential producers of …

The key role of interleukin-17 (IL-17) and T helper 17 (T H 17) cells in tissue inflammation,
autoimmunity and host defence led to the experimental targeting of these molecules in mouse …

Bacterial pneumonia is an increasing complication of HIV infection and inversely correlates
with the CD4 + lymphocyte count. Interleukin (IL)-17 is a cytokine produced principally by …

Emerging evidence supports the concept that T helper type 17 (T H 17) cells, in addition to
mediating autoimmunity, have key roles in mucosal immunity against extracellular pathogens. …

Steroid-resistant asthma comprises an important source of morbidity in patient populations.
TH 17 cells represent a distinct population of CD4+ Th cells that mediate neutrophilic …

Interleukin 23 (IL-23) and IL-17 have been linked to the pathogenesis of several chronic
inflammatory disorders, including inflammatory bowel disease. Yet as an important function for IL…

Interleukin 17 (IL-17) is a cytokine associated with inflammation, autoimmunity and defense
against some bacteria. Here we show that IL-17 can promote autoimmune disease through a …

Interleukin (IL)-23 is a heterodimeric cytokine that shares the identical p40 subunit as IL-12
but exhibits a unique p19 subunit similar to IL-12 p35. IL-12/23 p40, interferon γ (IFN-γ), and …

In this study, we examined the biological action of IL-17 on human non-small cell lung
cancer (NSCLC). Although IL-17 had no direct effect on the in vitro growth rate of NSCLC, IL-17 …