… maintained the participants database: Laura Ramos, Beatriz Lobo, Carmen Alonso, and
Marc Pigrau; designed and implemented the statistical analysis of the data: Jose Luis Mosquera …

Mitochondrial dysfunction is linked with the etiopathogenesis of Alzheimer disease and
Parkinson disease. Mitochondria are intracellular organelles essential for cell viability and are …

The epigenomic landscape of Parkinson's disease ( PD ) remains unknown. We performed a
genomewide DNA methylation and a transcriptome studies in induced pluripotent stem cell …

Adult zebrafish, in contrast to mammals, are able to regenerate their hearts in response to
injury or experimental amputation. Our understanding of the cellular and molecular bases that …

Cornelia de Lange syndrome (CdLS) is a rare disease affecting multiple organs and systems
during development. Mutations in the cohesin loader, NIPBL/Scc2, were first described and …

In vertebrates, GATA2 is a master regulator of hematopoiesis and is expressed throughout
embryo development and in adult life. Although the essential role of GATA2 in mouse …

The retinal extracellular matrix (ECM) provides architectural support, adhesion and signal
guidance that controls retinal development. Decellularization of the ECM affords great …

Myasthenia gravis (MG) is an autoimmune disease characterized by the presence of
autoantibodies, mainly against the acetylcholine receptor (AChR). The mechanisms triggering and …

Multiple transcription factors have been shown to promote pancreatic β-cell differentiation,
yet much less is known about negative regulators. Earlier epigenomic studies suggested that …

Schwannomatosis is an inherited disorder of Schwann cells of the peripheral nerves occurring
in the absence of bilateral vestibular schwannomas. The two main genes associated with …