[HTML][HTML] The cerebellum: a new key structure in the navigation system

C Rochefort, JM Lefort, L Rondi-Reig - Frontiers in neural circuits, 2013 - frontiersin.org
Early investigations of cerebellar function focused on motor learning, in particular on eyeblink
conditioning and adaptation of the vestibulo-ocular reflex, and led to the general view that …

[HTML][HTML] How the cerebellum may monitor sensory information for spatial representation

L Rondi-Reig, AL Paradis, JM Lefort… - Frontiers in systems …, 2014 - frontiersin.org
The cerebellum has already been shown to participate in the navigation function. We propose
here that this structure is involved in maintaining a sense of direction and location during …

[HTML][HTML] Breathing-driven prefrontal oscillations regulate maintenance of conditioned-fear evoked freezing independently of initiation

S Bagur, JM Lefort, MM Lacroix, G de Lavilléon… - Nature …, 2021 - nature.com
Brain–body interactions are thought to be essential in emotions but their physiological basis
remains poorly understood. In mice, regular 4 Hz breathing appears during freezing after …

Effect of sulforaphane in men with biochemical recurrence after radical prostatectomy

BG Cipolla, E Mandron, JM Lefort, Y Coadou… - Cancer prevention …, 2015 - AACR
Increases in serum levels of prostate-specific antigen (PSA) occur commonly in prostate
cancer after radical prostatectomy and are designated “biochemical recurrence.” Because the …

[PDF][PDF] Predictive maps in rats and humans for spatial navigation

…, EM Griesbauer, C Ghanamé, F Zisch, JM Lefort… - Current Biology, 2022 - cell.com
Much of our understanding of navigation comes from the study of individual species, often
with specific tasks tailored to those species. Here, we provide a novel experimental and …

[PDF][PDF] Hippocampal place cells encode global location but not connectivity in a complex space

…, A Harris, N Nyberg, F Donnarumma, JM Lefort… - Current Biology, 2021 - cell.com
Flexible navigation relies on a cognitive map of space, thought to be implemented by
hippocampal place cells: neurons that exhibit location-specific firing. In connected environments, …

Cerebellar contribution to spatial navigation: new insights into potential mechanisms

JM Lefort, C Rochefort, L Rondi-Reig… - The Cerebellum, 2015 - Springer
The contribution of the cerebellum to the non-motor aspects of spatial navigation is now
established, but the mechanisms of its participation remain unclear. The L7-PKCI mouse model, …

[HTML][HTML] Impaired cerebellar Purkinje cell potentiation generates unstable spatial map orientation and inaccurate navigation

JM Lefort, J Vincent, L Tallot, F Jarlier… - Nature …, 2019 - nature.com
Cerebellar activity supported by PKC-dependent long-term depression in Purkinje cells (PCs)
is involved in the stabilization of self-motion based hippocampal representation, but the …

[HTML][HTML] Harnessing olfactory bulb oscillations to perform fully brain-based sleep-scoring and real-time monitoring of anaesthesia depth

S Bagur, MM Lacroix, G de Lavilléon, JM Lefort… - PLoS …, 2018 - journals.plos.org
Real-time tracking of vigilance states related to both sleep or anaesthesia has been a goal
for over a century. However, sleep scoring cannot currently be performed with brain signals …

Dissociation of fear initiation and maintenance by breathing-driven prefrontal oscillations

S Bagur, JM Lefort, MM Lacroix, G de Lavilléon… - BioRxiv, 2018 - biorxiv.org
Does the body play an active role in emotions? Since the original James/Cannon controversy
this debate has mainly been fueled by introspective accounts of human experience. Here, …