The deliberate and orderly removal of cells by programmed cell death is a common phenomenon
during the development of metazoan animals. We have examined the distribution and …

Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical, …

In the present study we demonstrate that human monocytes activated by lipopolysaccharides
(LPS) were able to produce high levels of interleukin 10 (IL-10), previously designated …

A novel sequence discovered in a computational screen appears distantly related to the p35
subunit of IL-12. This factor, which we term p19, shows no biological activity by itself; instead…

A genomic interval at 75C1,2 is required for programmed cell death in Drosophila. We
identified a new activator of apoptosis, grim, which maps between two previously identified cell …

Osteoclasts, the cells that resorb bone, develop from hematopoietic precursors of the bone
marrow under the control of factors produced in their microenvironment. The cytokine …

Functional subsets of human T cells were delineated by analyzing patterns of lymphokines
produced by clones from individuals with leprosy and by T cell clones of known function. CD4 …

A gene, reaper (rpr), that appears to play a central control function for the initiation of programmed
cell death (apoptosis) in Drosophila was identified. Virtually all programmed cell death …

Cell death is essential for a plethora of physiological processes, and its deregulation
characterizes numerous human diseases. Thus, the in-depth investigation of cell death and its …

Compared with healthy tuberculin reactors, Mycobacterium tuberculosis-stimulated peripheral
blood mononuclear cells from tuberculosis patients had diminished production and mRNA …