[HTML][HTML] A primer on learning in Bayesian networks for computational biology

CJ Needham, JR Bradford, AJ Bulpitt… - PLoS computational …, 2007 - journals.plos.org
Bayesian networks (BNs) provide a neat and compact representation for expressing joint
probability distributions (JPDs) and for inference. They are becoming increasingly important in …

Inference in Bayesian networks

CJ Needham, JR Bradford, AJ Bulpitt… - Nature …, 2006 - nature.com
Bayesian networks are increasingly important for integrating biological data and for inferring
cellular networks and pathways. What are Bayesian networks and how are they used for …

Improved prediction of protein–protein binding sites using a support vector machines approach

JR Bradford, DR Westhead - Bioinformatics, 2005 - academic.oup.com
Motivation: Structural genomics projects are beginning to produce protein structures with
unknown function, therefore, accurate, automated predictors of protein function are required if …

The pulmonary circulation

JR Bradford, HP Dean - The Journal of physiology, 1894 - ncbi.nlm.nih.gov
I. HISTORY. Until the year 1871 itwas almost universally taught by physiologists that the
pulmonary vessels did not possess any vaso-motor system. In that year Brown-Sequardl …

[HTML][HTML] A comparison of massively parallel nucleotide sequencing with oligonucleotide microarrays for global transcription profiling

JR Bradford, Y Hey, T Yates, Y Li, SD Pepper, CJ Miller - BMC genomics, 2010 - Springer
Background RNA-Seq exploits the rapid generation of gigabases of sequence data by
Massively Parallel Nucleotide Sequencing, allowing for the mapping and digital quantification of …

Arabidopsis Co-expression Tool (ACT): web server tools for microarray-based gene expression analysis

…, JW Pinney, I Michalopoulos, JR Bradford… - Nucleic acids …, 2006 - academic.oup.com
The Arabidopsis Co-expression Tool, ACT, ranks the genes across a large microarray
dataset according to how closely their expression follows the expression of a query gene. A …

Insights into protein–protein interfaces using a Bayesian network prediction method

JR Bradford, CJ Needham, AJ Bulpitt… - Journal of molecular …, 2006 - Elsevier
Identifying the interface between two interacting proteins provides important clues to the
function of a protein, and is becoming increasing relevant to drug discovery. Here, surface patch …

The innervation of the renal blood vessels

JR Bradford - The Journal of Physiology, 1889 - ncbi.nlm.nih.gov
… arrested by torsion or ligature, the wound is packed with cotton wool, the kidney is then
placed in the oncometer, and the cannula in the carotid connected with the mercurial 1 Bradford

An extended set of PRDM1/BLIMP1 target genes links binding motif type to dynamic repression

…, MA Care, NJ Burgoyne, JR Bradford… - Nucleic acids …, 2010 - academic.oup.com
The transcriptional repressor B lymphocyte-induced maturation protein-1 (BLIMP1) regulates
gene expression and cell fate. The DNA motif bound by BLIMP1 in vitro overlaps with that …

[HTML][HTML] Whole transcriptome profiling of patient-derived xenograft models as a tool to identify both tumor and stromal specific biomarkers

JR Bradford, M Wappett, G Beran, A Logie… - Oncotarget, 2016 - ncbi.nlm.nih.gov
The tumor microenvironment is emerging as a key regulator of cancer growth and progression,
however the exact mechanisms of interaction with the tumor are poorly understood. …