Advances in genome sequencing reveal changes in gene content that contribute to arthropod macroevolution

AM Cheatle Jarvela, JR Wexler - Development Genes and Evolution, 2023 - Springer
Current sequencing technology allows for the relatively affordable generation of highly
contiguous genomes. Technological advances have made it possible for researchers to …

Pan-metazoan phylogeny of the DMRT gene family: a framework for functional studies

JR Wexler, DC Plachetzki, A Kopp - Development Genes and Evolution, 2014 - Springer
The family of Doublesex-Mab-3 Related Transcription factors (DMRTs) includes key
regulators of sexual differentiation and neurogenesis. To help understand the functional …

[HTML][HTML] The X chromosome of the German cockroach, Blattella germanica, is homologous to a fly X chromosome despite 400 million years divergence

RP Meisel, PJ Delclos, JR Wexler - BMC biology, 2019 - Springer
Background Sex chromosome evolution is a dynamic process that can proceed at varying
rates across lineages. For example, different chromosomes can be sex-linked between closely …

Impact of a system of computer-assisted diagnosis: initial evaluation of the hospitalized patient

JR Wexler, PT Swender… - American Journal of …, 1975 - jamanetwork.com
Computer-assisted diagnosis was evaluated for its ability to hasten the time to initial diagnosis
and reduce laboratory studies. The time to diagnosis averaged 2.8 days for a control …

Randomized trial of postoperative adjuvant chemotherapy with or without radiotherapy for carcinoma of the rectum: National Surgical Adjuvant Breast and Bowel …

…, M Wexler, D Prager, AB Cruz Jr… - Journal of the …, 2000 - academic.oup.com
BACKGROUND: The conviction that postoperative radiotherapy and chemotherapy represent
an acceptable standard of care for patients with Dukes' B (stage II) and Dukes' C (stage III) …

Second malignancies after Ewing's sarcoma: radiation dose-dependency of secondary sarcomas.

JF Kuttesch Jr, LH Wexler, RB Marcus… - Journal of Clinical …, 1996 - ascopubs.org
BACKGROUND An excess risk of second malignancies has been reported in survivors of
Ewing's sarcoma. We examined a multiinstitutional data base to reevaluate the risk among …

The discovery of a new class of highly specific nonpeptide angiotensin II receptor antagonists

…, PC Wong, AL Johnson, RR Wexler - American journal of …, 1991 - academic.oup.com
Since angiotensin II (AII) is the effector molecule of the renin angiotensin system, the most
direct approach to interfere with this system would be to antagonize AII at the level of its …

In vivo pharmacology of DuP 753

…, JV Duncia, DJ Carini, RR Wexler… - American journal of …, 1991 - academic.oup.com
A review of the in vivo pharmacology of DuP 753 (2-n-butyl-4-chloro-5-hydroxymethyl-1-[(2’-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazole,
potassium salt) is presented. In the pithed …

Spiral CT of renal artery stenosis: comparison of three-dimensional rendering techniques.

…, RB Jeffrey Jr, CH McDonnell, FG Sommer, L Wexler… - Radiology, 1994 - pubs.rsna.org
PURPOSE: To evaluate the accuracy of computed tomographic (CT) angiography in the
detection of renal artery stenosis (RAS). MATERIALS AND METHODS: CT angiography was …

Measurement of the neutron lifetime using a magneto-gravitational trap and in situ detection

…, PL Walstrom, Z Wang, W Wei, HL Weaver, JW Wexler… - Science, 2018 - science.org
The precise value of the mean neutron lifetime, τ n , plays an important role in nuclear and
particle physics and cosmology. It is used to predict the ratio of protons to helium atoms in the …