Understanding anthelmintic resistance: the need for genomics and genetics
JS Gilleard - International journal for parasitology, 2006 - Elsevier
… (JS Gilleard and J. Smith, unpublished data). The presence of only 11 chromosomes in
some embryos is consistent with an XX/XO basis of sex determination and so the karyotype …
some embryos is consistent with an XX/XO basis of sex determination and so the karyotype …
[HTML][HTML] Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor …
Anthelmintic resistance has a great impact on livestock production systems worldwide, is an
emerging concern in companion animal medicine, and represents a threat to our ongoing …
emerging concern in companion animal medicine, and represents a threat to our ongoing …
[HTML][HTML] World Association for the Advancement of Veterinary Parasitology (WAAVP) guideline for diagnosing anthelmintic resistance using the faecal egg count …
The faecal egg count reduction test (FECRT) remains the method of choice for establishing
the efficacy of anthelmintic compounds in the field, including the diagnosis of anthelmintic …
the efficacy of anthelmintic compounds in the field, including the diagnosis of anthelmintic …
[HTML][HTML] The genome and transcriptome of Haemonchus contortus, a key model parasite for drug and vaccine discovery
…, A Wolstenholme, M Berriman, JS Gilleard… - Genome biology, 2013 - Springer
Background The small ruminant parasite Haemonchus contortus is the most widely used
parasitic nematode in drug discovery, vaccine development and anthelmintic resistance …
parasitic nematode in drug discovery, vaccine development and anthelmintic resistance …
[HTML][HTML] Exploring the gastrointestinal “nemabiome”: deep amplicon sequencing to quantify the species composition of parasitic nematode communities
…, R Lewis, TA Yazwinski, JD Wasmuth, JS Gilleard - PLoS …, 2015 - journals.plos.org
Parasitic helminth infections have a considerable impact on global human health as well as
animal welfare and production. Although co-infection with multiple parasite species within a …
animal welfare and production. Although co-infection with multiple parasite species within a …
cis Regulatory Requirements for Hypodermal Cell-Specific Expression of the Caenorhabditis elegans Cuticle Collagen Gene dpy-7
JS Gilleard, JD Barry, IL Johnstone - Molecular and cellular biology, 1997 - Taylor & Francis
The Caenorhabditis elegans cuticle collagens are encoded by a multigene family of between
50 and 100 members and are the major component of the nematode cuticular exoskeleton. …
50 and 100 members and are the major component of the nematode cuticular exoskeleton. …
Population genetics of anthelmintic resistance in parasitic nematodes
JS Gilleard, RN Beech - Parasitology, 2007 - cambridge.org
A key aim of anthelmintic resistance research is to identify molecular markers that could form
the basis of sensitive and accurate diagnostic tests. These would provide powerful tools to …
the basis of sensitive and accurate diagnostic tests. These would provide powerful tools to …
Haemonchus contortus as a paradigm and model to study anthelmintic drug resistance
JS Gilleard - Parasitology, 2013 - cambridge.org
… Tait and JS Gilleard, unpublished). These concepts are summarized in Fig. 2. … Tait and
JS Gilleard, unpublished). We hypothesize that these findings are due to the complex …
JS Gilleard, unpublished). We hypothesize that these findings are due to the complex …
[HTML][HTML] The emergence of resistance to the benzimidazole anthlemintics in parasitic nematodes of livestock is characterised by multiple independent hard and soft …
…, PJ Skuce, F Jackson, JS Gilleard - PLoS neglected …, 2015 - journals.plos.org
Anthelmintic resistance is a major problem for the control of parasitic nematodes of livestock
and of growing concern for human parasite control. However, there is little understanding of …
and of growing concern for human parasite control. However, there is little understanding of …
[HTML][HTML] Multiple drug resistance in the canine hookworm Ancylostoma caninum: an emerging threat?
…, SB Howell, JJ Schaefer, RW Avramenko, JS Gilleard… - Parasites & vectors, 2019 - Springer
Background The canine hookworm, Ancylostoma caninum is the most prevalent and important
intestinal nematode parasite of dogs in the USA. Hookworms are typically well controlled …
intestinal nematode parasite of dogs in the USA. Hookworms are typically well controlled …