Infection by certain human papillomavirus types is regarded as the major risk factor in the
development of cervical cancer, one of the most common cancers of women worldwide. …

The human papillomavirus types (HPVs) most often associated with cancer of the cervix,
such as HPV16, have been reported previously to immortalize normal human foreskin …

Background Oncogenic human papillomaviruses (HPVs), especially HPV type 16 (HPV-16),
cause anogenital epithelial cancers and are suspected of causing epithelial cancers of the …

The L1 genes of two human papillomavirus type 16 (HPV16) isolates derived from
condylomata acuminata were used to express the L1 major capsid protein in insect cells via …

End of study analyses of the phase III trials of prophylactic human papillomavirus (HPV)
virus-like particle (VLP) vaccines in young women are now largely completed. Two distinct …

Background: Studies in animal models have shown that systemic immunization with a
papillomavirus virus-like particle (VLP) vaccine composed of L1, a major structural viral protein, …

… Financial Disclosures: Drs Schiller and Lowy report that they are named inventors on US
government–owned HPV vaccine patents that are licensed to GSK and Merck and are entitled …

Infection with human papillomavirus (HPV) is recognized as one of the major causes of
infection-related cancer worldwide, as well as the causal factor in other diseases. Strong …

We tested the ability of vaccination with virus-like particles (VLPs) to protect domestic rabbits
against papillomas induced by the cottontail rabbit papillomavirus (CRPV). A recombinant …

Human papillomavirus (HPV) infection causes virtually all cases of cervical cancer, the
second most common cause of death from cancer among women worldwide. This Review …