… Bonventre is coinventor on … Bonventre family has received income for consulting from
Genzyme, Celgene, Sanofi-Avenits, Gilead, Merck, and PTC Therapeutics; in addition, Bonventre is …

As covered in the preceding sections, acute renal failure (ARF) is a syndrome associated with
high mortality in humans. Current therapy is limited to supportive measures and preventive …

Ischemic acute renal failure: An inflammatory disease? Inflammation plays a major role in
the pathophysiology of acute renal failure resulting from ischemia. In this review, we discuss …

The marginal effects of acute kidney injury on in-hospital mortality, length of stay (LOS), and
costs have not been well described. A consecutive sample of 19,982 adults who were …

Kidney Injury Molecule-1 (KIM-1): A novel biomarker for human renal proximal tubule injury.
Background Traditional blood and urine markers for the diagnosis of various renal diseases …

Fibrosis is responsible for chronic progressive kidney failure, which is present in a large
number of adults in the developed world. It is increasingly appreciated that acute kidney injury (…

Inflammation causes the induction of cyclooxygenase-2 (Cox-2) 1 , leading to the release of
prostanoids, which sensitize peripheral nociceptor terminals and produce localized pain …

We report the identification of rat and human cDNAs for a type 1 membrane protein that
contains a novel six-cysteine immunoglobulin-like domain and a mucin domain; it is named …

Understanding the origin of myofibroblasts in kidney is of great interest because these cells
are responsible for scar formation in fibrotic kidney disease. Recent studies suggest …

Parathyroid hormone (PTH), a major regulator of mineral ion metabolism, and PTH-related
peptide (PTHrP), which causes hypercalcemia in some cancer patients, stimulate multiple …