The replacement of conventional antimalarial drugs with high-cost, artemisinin-based
alternatives has created a gap in the successful management of malaria. This gap reflects an …

… On the other hand, some data suggest that one of the eleven msp3 genes may be over
expressed relative to the others (Jiang, Barnwell & Galinski, unpublished data) and this could be …

Malaria rapid diagnostic tests (RDTs) emerged in the early 1990s into largely unregulated
markets, and uncertain field performance was a major concern for the acceptance of tests for …

The human malaria parasite Plasmodium vivax is responsible for 25–40% of the ∼515 million
annual cases of malaria worldwide. Although seldom fatal, the parasite elicits severe and …

We have identified strain-specific antigens with Camp and St. Lucia strains of P. falciparum
of Mr approximately 285,000 and approximately 260,000, respectively. These strain-specific …

Background . Malaria in humans is caused by apicomplexan parasites belonging to 5 species
of the genus Plasmodium. Infections with Plasmodium ovale are widely distributed but …

In light of the recent controversies over the role of animal models for research into the
development of new treatments for severe malaria, particularly cerebral disease, a group of …

Background Malaria rapid diagnostic tests (RDTs) offer significant potential to improve the
diagnosis of malaria, and are playing an increasing role in malaria case management, control …

… At 1 mM concentrations, these peptides did not inhibit cytoadherence (Barnwell J.,
unpublished observation), whereas the CSVTCG peptide does inhibit the interaction of GP88 and …

Plasmodium vivax merozoites primarily invade reticulocytes. The basis of this restricted host
cell preference has been debated. Here we introduce two novel P. vivax proteins that …