A method is described for searching protein sequence databases using tandem mass spectra
of tryptic peptides. The approach uses a de novo sequencing algorithm to derive a short …

There are several computer programs that can match peptide tandem mass spectrometry
data to their exactly corresponding database sequences, and in most protein identification …

Importance There is limited evidence on the optimal strategy for liberating infants and
children from invasive mechanical ventilation in the pediatric intensive care unit. Objective To …

We demonstrate the use of a Generative Adversarial Network (GAN), trained from a set of
over 400,000 light and heavy chain human antibody sequences, to learn the rules of human …

High throughput protein analysis (ie, proteomics) first became possible when sensitive
peptide mass mapping techniques were developed, thereby allowing for the possibility of …

There are many computer programs that can match tandem mass spectra of peptides to
database-derived sequences; however, situations can arise where mass spectral data cannot be …

Photoactivated rhodopsin (Rho∗) is phosphorylated near the C terminus at multiple sites,
predominantly at Ser 334 , Ser 338 , and Ser 343 . We systematically examined the sites of …

Despite recent advances in qualitative proteomics, the automatic identification of peptides
with optimal sensitivity and accuracy remains a difficult goal. To address this deficiency, a …

A computer program, Sherpa, has been implemented to aid in the elucidation of electrospray
ionization liquid chromatography/mass spectrometry (LC/MS) and tandem mass …

The initial stages of tandem mass spectral data interpretation for a pro-teomics project
usually involve looking for exact matches between the query spectrum and theoretical …