[HTML][HTML] Long non-coding RNAs in the regulation of gene expression: physiology and disease
The identification of RNAs that are not translated into proteins was an important breakthrough,
defining the diversity of molecules involved in eukaryotic regulation of gene expression. …
defining the diversity of molecules involved in eukaryotic regulation of gene expression. …
Two pathways for lysophosphatidic acid production
J Aoki, A Inoue, S Okudaira - … et Biophysica Acta (BBA)-Molecular and Cell …, 2008 - Elsevier
Lysophosphatidic acid (LPA, 1- or 2-acyl-sn-glycerol 3-phosphate) is a simple phospholipid
but displays an intriguing cell biology that is mediated via interactions with G protein-…
but displays an intriguing cell biology that is mediated via interactions with G protein-…
Mechanisms of lysophosphatidic acid production
J Aoki - Seminars in cell & developmental biology, 2004 - Elsevier
Lysophosphatidic acid is one of the most attractive phospholipid mediator with multiple
biological functions and is implicated in various human diseases. In the past ten years much has …
biological functions and is implicated in various human diseases. In the past ten years much has …
Effect of renal denervation on blood pressure in the presence of antihypertensive drugs: 6-month efficacy and safety results from the SPYRAL HTN-ON MED proof-of …
…, S Brar, SA Cohen, M Fahy, G Pilcher, K Kario, J Aoki… - The Lancet, 2018 - thelancet.com
Background Previous catheter-based renal denervation studies have reported variable
efficacy results. We aimed to evaluate safety and blood pressure response after renal …
efficacy results. We aimed to evaluate safety and blood pressure response after renal …
Endothelial progenitor cell capture by stents coated with antibody against CD34: the HEALING-FIM (Healthy Endothelial Accelerated Lining Inhibits Neointimal Growth …
J Aoki, PW Serruys, H van Beusekom, ATL Ong… - Journal of the American …, 2005 - jacc.org
Objectives : This study was designed to evaluate whether rapid endothelialization of stainless
steel stents with a functional endothelium prevents stent thrombosis and reduces the …
steel stents with a functional endothelium prevents stent thrombosis and reduces the …
Catheter-based renal denervation in patients with uncontrolled hypertension in the absence of antihypertensive medications (SPYRAL HTN-OFF MED): a randomised …
…, M Fahy, DE Jones, M Rothman, M Böhm, J Aoki… - The Lancet, 2017 - thelancet.com
Background Previous randomised renal denervation studies did not show consistent efficacy
in reducing blood pressure. The objective of our study was to evaluate the effect of renal …
in reducing blood pressure. The objective of our study was to evaluate the effect of renal …
Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production
Autotaxin (ATX) is a tumor cell motility–stimulating factor, originally isolated from melanoma
cell supernatants. ATX had been proposed to mediate its effects through 5′-nucleotide …
cell supernatants. ATX had been proposed to mediate its effects through 5′-nucleotide …
[HTML][HTML] Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures
A comprehensive and standardized system to report lipid structures analyzed by MS is
essential for the communication and storage of lipidomics data. Herein, an update on both the …
essential for the communication and storage of lipidomics data. Herein, an update on both the …
Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARγ agonist
…, GA Zimmerman, K Hama, J Aoki… - Proceedings of the …, 2003 - National Acad Sciences
Lysophosphatidic acid (LPA) is a pluripotent lipid mediator acting through plasma
membrane-associated LPA x receptors that transduce many, but not all, of its effects. We identify …
membrane-associated LPA x receptors that transduce many, but not all, of its effects. We identify …
LPA3-mediated lysophosphatidic acid signalling in embryo implantation and spacing
Every successful pregnancy requires proper embryo implantation. Low implantation rate is a
major problem during infertility treatments using assisted reproductive technologies 1 . Here …
major problem during infertility treatments using assisted reproductive technologies 1 . Here …