Understanding how a subset of expressed genes dictates cellular phenotype is a considerable
challenge owing to the large numbers of molecules involved, their combinatorics and the …

Background Riociguat and phosphodiesterase-5 inhibitors (PDE5i), approved for the
treatment of pulmonary arterial hypertension (PAH), act on the same pathway via different …

We present a CRISPR/Cas9 genome-editing strategy to systematically tag endogenous proteins
with fluorescent tags in human induced pluripotent stem cells (hiPSC). To date, we have …

Historically, spontaneous deletions and insertions have provided means to probe germline
developmental genetics in Drosophila, mouse and other species. Here, induced pluripotent …

BACKGROUND: Delayed postexercise heart rate recovery (HRR) has been associated with
disability and poor prognosis in chronic cardiopulmonary diseases. The usefulness of HRR …

BACKGROUND: In hypersensitivity pneumonitis (HP), survival can be predicted on the basis
of the severity of fibrosis in surgical lung biopsy, but few data are available on the influence …

Electrochromic films of NiO x and WO x were produced by the spray pyrolysis technique.
The nickel-oxide-based coatings were obtained from an aqueous solution of nickel nitrate. …

To produce abundant cell culture samples to generate large, standardized image datasets
of human induced pluripotent stem (hiPS) cells, we developed an automated workflow on a …

We describe a multistep method for endogenous tagging of transcriptionally silent genes in
human induced pluripotent stem cells (hiPSCs). A monomeric EGFP (mEGFP) fusion tag and …

We performed a comprehensive analysis of the transcriptional changes occurring during
human induced pluripotent stem cell (hiPSC) differentiation to cardiomyocytes. Using single cell …