The formation of sharp borders, across which cell intermingling is restricted, has a crucial
role in the establishment and maintenance of organized tissues. Signaling of Eph receptors …

Dorsoventral patterning of the vertebrate nervous system is achieved by the combined activity
of morphogenetic signals secreted from dorsal and ventral signalling centres. The Shh/Gli …

The secreted ligand Sonic Hedgehog (Shh) organizes the pattern of cellular differentiation
in the ventral neural tube. For the five neuronal subtypes, increasing levels and durations of …

During CNS development, the proliferation of progenitors must be coordinated with the pattern
of neuronal subtype generation. In the ventral neural tube, Sonic hedgehog acts as a long …

The Simons Observatory (SO) is a ground-based cosmic microwave background (CMB)
experiment sited on Cerro Toco in the Atacama Desert in Chile that promises to provide …

The entire vertebrate nervous system develops from a simple epithelial sheet, the neural
plate which, along development, acquires the large number and wide variety of neuronal cell …

Sonic hedgehog signalling is essential for the embryonic development of many tissues
including the central nervous system, where it controls the pattern of cellular differentiation. A …

The question of what gravitational theory could supersede General Relativity has been
central in theoretical physics for decades. Many disparate alternatives have been proposed …

Positioning organs in the body often requires the movement of multiple tissues, yet the molecular
and cellular mechanisms coordinating such movements are largely unknown. Here, we …

The patterning of tissues to form subdivisions with distinct and homogeneous regional
identity is potentially disrupted by cell intermingling. Transplantation studies suggest that …