Adverse environmental conditions trigger C. elegans larvae to activate an alternative
developmental program, termed dauer diapause, which renders them stress resistant. High-level …

10.7554/eLife.19887.001 Neuromodulators shape neural circuit dynamics. Combining
electron microscopy, genetics, transcriptome profiling, calcium imaging, and optogenetics, we …

Oxidative energy metabolism is depressed after mild/moderate traumatic brain injury (TBI)
during early development, accompanied by behavioral debilitation and secondary neuronal …

Pathophysiology of developmental traumatic brain injury (TBI) is unique due to intrinsic
differences in the developing brain. Energy metabolic studies of the brain during early …

Because the presence of pain impedes motor recovery in individuals with spinal cord injury (SCI),
it is necessary to understand their supraspinal substrates in translational animal …

A neuronal F‐box protein FSN‐1 regulates Caenorhabditis elegans neuromuscular junction
development by negatively regulating DLK‐mediated MAPK signalling. In the present study, …

Traumatic brain injury (TBI) in general has varied neuropathological consequences depending
upon the intensity and biomechanics of the injury. Furthermore, in pediatric TBI, intrinsic …

Targeting mitochondrial ion homeostasis using Kaempferol, a mitochondrial Ca 2+ uniporter
channel activator, improves energy metabolism and behavior soon after a traumatic brain …

… and is consistently expressed in muscles and neurons (Chitturi et al, 2018). Previously, we
… H–J. No obvious change in the fluorescence levels of DVB neuron between wild type and …

Mechanisms that regulate apoptosis in a temporal and lineage-specific manner remain poorly
understood. The COE (Collier/Olf/EBF) transcription factors have been implicated in the …