User profiles for J. Dhawan

Jyotsna Dhawan

Center for Cellular and Molecular Biology
Verified email at ccmb.res.in
Cited by 3535

Stem cells in postnatal myogenesis: molecular mechanisms of satellite cell quiescence, activation and replenishment

J Dhawan, TA Rando - Trends in cell biology, 2005 - cell.com
Satellite cells are the primary stem cells in adult skeletal muscle, and are responsible for
postnatal muscle growth, hypertrophy and regeneration. In mature muscle, most satellite cells …

Concise review: quiescence in adult stem cells: biological significance and relevance to tissue regeneration

M Rumman, J Dhawan, M Kassem - Stem cells, 2015 - academic.oup.com
… Over-expression of NICD in mouse MuSCs, suppresses proliferation and preserves self-renewal
ability while inhibiting myogenic differentiation in vitro [83], whereas loss of RBP-J, a …

Exosomes: mobile platforms for targeted and synergistic signaling across cell boundaries

N Vyas, J Dhawan - Cellular and molecular life sciences, 2017 - Springer
Intercellular communications play a vital role during tissue patterning, tissue repair, and
immune reactions, in homeostasis as well as in disease. Exosomes are cell-derived secreted …

[HTML][HTML] Evidence of oxidative stress in mdx mouse muscle: studies of the pre-necrotic state

MH Disatnik, J Dhawan, Y Yu, MF Beal… - Journal of the …, 1998 - Elsevier
Considerable evidence indicates that free radical injury may underlie the pathologic changes
in muscular dystrophies from mammalian and avian species. We have investigated the …

[HTML][HTML] Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties

…, AL Cicero, G Raposo, D Palakodeti, J Dhawan - Scientific reports, 2014 - nature.com
Hedgehog (Hh) is a secreted morphogen that elicits differentiation and patterning in developing
tissues. Multiple proposed mechanisms to regulate Hh dispersion includes lipoprotein …

Systemic delivery of human growth hormone by injection of genetically engineered myoblasts

J Dhawan, LC Pan, GK Pavlath, MA Travis, AM Lanctot… - Science, 1991 - science.org
… Brabac for assistance with embedding and staining ofthe muscle sections; J. Wilson, C. …
Parmacek for discussions and advice; J. Wilson for the BAG retrovirus; and K. Dekker for help …

MLL5, a trithorax homolog, indirectly regulates H3K4 methylation, represses cyclin A2 expression, and promotes myogenic differentiation

…, P Kandalla, GK Pavlath, J Dhawan - Proceedings of the …, 2009 - National Acad Sciences
Most cells in adult tissues are nondividing. In skeletal muscle, differentiated myofibers have
exited the cell cycle permanently, whereas satellite stem cells withdraw transiently, returning …

Noncultured extracted hair follicle outer root sheath cell suspension for transplantation in vitiligo

S Mohanty, A Kumar, J Dhawan… - British Journal of …, 2011 - academic.oup.com
Background Current noncultured cell‐based transplantation therapies for vitiligo largely involve
shave skin biopsy for preparation of noncultured melanocyte suspension. As the overall …

Insulin resistance, high prevalence of diabetes, and cardiovascular risk in immigrant Asians. Genetic or environmental effect?

J Dhawan, CL Bray, R Warburton, DS Ghambhir… - Heart, 1994 - heart.bmj.com
OBJECTIVES--To compare the prevalence of diabetes, hyperinsulinaemia, and associated
metabolic abnormalities in immigrant Asians, Asians in India, and native white British men. …

[HTML][HTML] Role of actin filaments in correlating nuclear shape and cell spreading

…, S Raghavan, C Kuyyamudi, A Majumder, J Dhawan… - PloS one, 2014 - journals.plos.org
… (f–j) Similar observations of a cell spread on a soft substrate (3 kPa). Note the difference in
the … Images in k and l are 3D reconstructions of the cells shown in a–e and f–j respectively. …