The lymphatic system plays an important role in human circulation and organ perfusion
homeostasis (1). Disorders of the pulmonary lymphatic system occur in a variety of clinical …

Obesity is associated with the development of asthma, which is often difficult to control. To
understand the immunological pathways that lead to obesity-associated asthma, we fed mice …

The last decades of neuroscience research have produced immense progress in the methods
available to understand brain structure and function. Social, cognitive, clinical, affective, …

Background Bronchial asthma is associated with an inflammatory process that is characterized
by the presence in the airways of large numbers of CD4+ T cells producing interleukin-4 …

Background— Pulmonary vascular injury by toxins can induce neointimal formation, pulmonary
arterial hypertension (PAH), right ventricular failure, and death. We showed previously …

Obesity is heritable and predisposes to many diseases. To understand the genetic basis of
obesity better, here we conduct a genome-wide association study and Metabochip meta-…

Vitamin D deficiency (VDD) is highly prevalent worldwide. The classical role for vitamin D is
to regulate calcium absorption form the gastrointestinal tract and influence bone health. …

Hypertensive pulmonary vascular disease is characterized by abnormal proliferation of
vascular endothelial and smooth muscle cells, leading to occlusion of pulmonary arterioles, …

Tobacco and alcohol use are leading causes of mortality that influence risk for many complex
diseases and disorders 1 . They are heritable 2 , 3 and etiologically related 4 , 5 behaviors …

The Health and Retirement Study (HRS) is a nationally representative longitudinal survey of
more than 37 000 individuals over age 50 in 23 000 households in the USA. The survey, …