… [46] San Miguel-Ruiz JE, García-Arrarás JE. Common cellular events occur during wound …
[47] Candelaria AG, Murray G, File SK, García-Arrarás JE. Contribution of mesenterial muscle …

Holothurians, or sea cucumbers, exhibit two processes that have intrigued biologists for
decades: autotomy and regeneration. Autotomy includes the loss of body parts by evisceration …

… Note that the ingressed cells are positively labeled with Meso1 antibody (green), which has
been shown to be a specific marker of mesothelial cells in sea cucumbers (García-Arrarás et …

Syntaxins A and B are nervous system-specific proteins implicated in the docking of synaptic
vesicles with the presynaptic plasma membrane. A family of syntaxin-related proteins from …

… 2A), also described as serosa in our previous studies (García-Arrarás et al., ’91a,b; Díaz-Miranda
et al., ’95, ’96). In transverse sections of the large intestine the width of this layer is 19.6 …

Background Among deuterostomes, the regenerative potential is maximally expressed in
echinoderms, animals that can quickly replace most injured organs. In particular, sea …

Background All animals possess some type of tissue repair mechanism. In some species,
the capacity to repair tissues is limited to the healing of wounds. Other species, such as …

Background Echinoderms are emerging as important models in regenerative biology. Significant
amount of data are available on cellular mechanisms of post-traumatic repair in these …

The sea cucumber, Holothuria glaberrima, has the capacity to regenerate its internal organs.
Intestinal regeneration is accomplished by the thickening of the mesenteric border and the …

Echinoderms possess a variety of cells populating the coelomic fluid; these cells are
responsible for mounting defense against foreign agents. In the sea cucumber Holothuria …