User profiles for J. Grosshans

Jörg Großhans

Philipps University
Verified email at uni-marburg.de
Cited by 3480

[HTML][HTML] Forces directing germ-band extension in Drosophila embryos

D Kong, F Wolf, J Großhans - Mechanisms of development, 2017 - Elsevier
… Two vertices are labeled with indices i and j. The connecting junction's length l ij is indicated…
of cell α, line tension of junction (i, j) and perimeter contractility of cell α, respectively. L α …

[HTML][HTML] A genetic link between morphogenesis and cell division during formation of the ventral furrow in Drosophila

J Großhans, E Wieschaus - Cell, 2000 - cell.com
Stages in development with rapid transitions between mitosis and morphogenesis may require
specific mechanisms to coordinate cell shape change. Here we describe a novel mitotic …

[PDF][PDF] In vivo mapping of hydrogen peroxide and oxidized glutathione reveals chemical and regional specificity of redox homeostasis

SC Albrecht, AG Barata, J Großhans, AA Teleman… - Cell metabolism, 2011 - cell.com
The glutathione redox couple (GSH/GSSG) and hydrogen peroxide (H 2 O 2 ) are central to
redox homeostasis and redox signaling, yet their distribution within an organism is difficult to …

Resolution doubling in fluorescence microscopy with confocal spinning-disk image scanning microscopy

…, J Großhans, G Bunt, J Enderlein - Proceedings of the …, 2013 - National Acad Sciences
We demonstrate how a conventional confocal spinning-disk (CSD) microscope can be converted
into a doubly resolving image scanning microscopy (ISM) system without changing any …

Dynamics of cortical domains in early Drosophila development

A Schmidt, J Grosshans - Journal of cell science, 2018 - journals.biologists.com
Underlying the plasma membrane of eukaryotic cells is an actin cortex that includes actin
filaments and associated proteins. A special feature of all polarized and epithelial cells are …

Positive feedback between Dia1, LARG, and RhoA regulates cell morphology and invasion

…, S Hannemann, OT Fackler, J Großhans… - Genes & …, 2007 - genesdev.cshlp.org
The RhoA-effector Dia1 controls actin-dependent processes such as cytokinesis, SRF
transcriptional activity, and cell motility. Dia1 polymerizes actin through its formin homology (FH) 2 …

[HTML][HTML] Oligomerisation of Tube and Pelle leads to nuclear localisation of dorsal

J Großhans, F Schnorrer, C Nüsslein-Volhard - Mechanisms of …, 1999 - Elsevier
In the Drosophila embryo the nuclear localisation of Dorsal, a member of the Rel family, is
regulated by an extracellular signal, which is transmitted to the interior of the egg cell by a …

Cytoskeletal mechanics and dynamics in the Drosophila syncytial embryo

…, IA Telley, J Großhans - Journal of Cell …, 2021 - journals.biologists.com
Cell and tissue functions rely on the genetic programmes and cascades of biochemical signals.
It has become evident during the past decade that the physical properties of soft material …

RhoGEF2 and the formin Dia control the formation of the furrow canal by directed actin assembly during Drosophila cellularisation

J Großhans, C Wenzl, HM Herz, S Bartoszewski… - 2005 - journals.biologists.com
The physical interaction of the plasma membrane with the associated cortical cytoskeleton
is important in many morphogenetic processes during development. At the end of the …

[PDF][PDF] Developmental control of nuclear size and shape by Kugelkern and Kurzkern

…, F Pilot, N Vogt, T Lecuit, G Krohne, J Großhans - Current biology, 2006 - cell.com
Background The shape of a nucleus depends on the nuclear lamina, which is tightly associated
with the inner nuclear membrane and on the interaction with the cytoskeleton. However, …