Background We present the results of EGASP, a community experiment to assess the state-of-the-art
in genome annotation within the ENCODE regions, which span 1% of the human …

Eukaryotic cells make many types of primary and processed RNAs that are found either in
specific subcellular compartments or throughout the cells. A complete catalogue of these …

The GENCODE Consortium aims to identify all gene features in the human genome using a
combination of computational analysis, manual annotation, and experimental validation. …

Scientists have been trying to identify every gene in the human genome since the initial draft
was published in 2001. In the years since, much progress has been made in identifying …

The human genome contains many thousands of long noncoding RNAs (lncRNAs). While
several studies have demonstrated compelling biological and disease roles for individual …

Ensembl ( http://www.ensembl.org ) creates tools and data resources to facilitate genomic
analysis in chordate species with an emphasis on human, major vertebrate model organisms …

Gene targeting in embryonic stem cells has become the principal technology for manipulation
of the mouse genome, offering unrivalled accuracy in allele design and access to …

Ensembl ( http://www.ensembl.org ) is a genomic interpretation system providing the most up-to-date
annotations, querying tools and access methods for chordates and key model …

The Ensembl project ( http://www.ensembl.org ) is a system for genome annotation, analysis,
storage and dissemination designed to facilitate the access of genomic annotation from …

Genome-sequencing studies indicate that all humans carry many genetic variants predicted
to cause loss of function (LoF) of protein-coding genes, suggesting unexpected redundancy …