User profiles for J. Havel

Jonathan Havel

- Verified email at volastratx.com - Cited by 13822

John Havel

- Verified email at missouristate.edu - Cited by 5260

The evolving landscape of biomarkers for checkpoint inhibitor immunotherapy

JJ Havel, D Chowell, TA Chan - Nature Reviews Cancer, 2019 - nature.com
Checkpoint inhibitor-based immunotherapies that target cytotoxic T lymphocyte antigen 4 (CTLA4)
or the programmed cell death 1 (PD1) pathway have achieved impressive success in …

[HTML][HTML] Aquatic invasive species: challenges for the future

JE Havel, KE Kovalenko, SM Thomaz, S Amalfitano… - Hydrobiologia, 2015 - Springer
Humans have effectively transported thousands of species around the globe and, with
accelerated trade; the rate of introductions has increased over time. Aquatic ecosystems seem at …

[PDF][PDF] Gold and nano-gold in medicine: overview, toxicology and perspectives.

NR Panyala, EM Peña-Méndez, J Havel - Journal of applied …, 2009 - jab.zsf.jcu.cz
… Houška J, Alberti M, Havel J: Laser ablation synthesis of phosphorus sulphides, selenides
and ternary PpSqSer clusters from various precursors. Rapid Commun Mass Spectrom 22:417…

Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer

…, P Kvistborg, V Makarov, JJ Havel, W Lee, J Yuan… - Science, 2015 - science.org
Immune checkpoint inhibitors, which unleash a patient’s own T cells to kill tumors, are
revolutionizing cancer treatment. To unravel the genomic determinants of response to this therapy, …

[PDF][PDF] Tumor and microenvironment evolution during immunotherapy with nivolumab

N Riaz, JJ Havel, V Makarov, A Desrichard, WJ Urba… - Cell, 2017 - cell.com
The mechanisms by which immune checkpoint blockade modulates tumor evolution during
therapy are unclear. We assessed genomic changes in tumors from 68 patients with …

Artificial neural networks in medical diagnosis

…, P Vaňhara, A Hampl, J Havel - Journal of applied …, 2013 - Elsevier
… 5 becomes: (6) Δ w i j k = − η d E d w i j + μ Δ w i j k − 1 where μ is the “momentum” term
and Δw ij k-1 is the change of the weight w ij from the (k-1)- th learning cycle. The learning rate …

[HTML][HTML] The head and neck cancer immune landscape and its immunotherapeutic implications

R Mandal, Y Şenbabaoğlu, A Desrichard, JJ Havel… - JCI insight, 2016 - ncbi.nlm.nih.gov
Recent clinical trials have demonstrated a clear survival advantage in advanced head and
neck squamous cell carcinoma (HNSCC) patients treated with immune checkpoint blockade. …

[PDF][PDF] Humic substances-compounds of still unknown structure: applications in agriculture, industry, environment, and biomedicine

EM Peña-Méndez, J Havel, J Patočka - J. Appl. Biomed, 2005 - jab.zsf.jcu.cz
… and Havel J.: Capillary zone electrophoresis for the separation and characterization of …
Pacheco ML and J. Havel: Capillary zone electrophoresis of humic acids from American continent…

[PDF][PDF] Silver or silver nanoparticles: a hazardous threat to the environment and human health?

NR Panyala, EM Peña-Méndez, J Havel - Journal of applied …, 2008 - jab.zsf.jcu.cz
… Cheng D, Yang J, Zhao Y: Antibacterial materials of silver nanoparticles application in …
Zhang Y, Chen F, Zhuang J: Synthesis of silver nanoparticles via electrochemical reduction on …

Flooding to restore connectivity of regulated, large-river wetlands: natural and controlled flooding as complementary processes along the lower Missouri River

…, JR Bodie, J Dohrenwend, GT Gelwicks, JE Havel… - …, 1998 - academic.oup.com
You can always count on finding the Mississippi just where you left it last year. But the
Missouri is a tawny, restless, brawling flood. It cuts corners, runs around at night, fills itself with …