The evolving landscape of biomarkers for checkpoint inhibitor immunotherapy
Checkpoint inhibitor-based immunotherapies that target cytotoxic T lymphocyte antigen 4 (CTLA4)
or the programmed cell death 1 (PD1) pathway have achieved impressive success in …
or the programmed cell death 1 (PD1) pathway have achieved impressive success in …
[HTML][HTML] Aquatic invasive species: challenges for the future
Humans have effectively transported thousands of species around the globe and, with
accelerated trade; the rate of introductions has increased over time. Aquatic ecosystems seem at …
accelerated trade; the rate of introductions has increased over time. Aquatic ecosystems seem at …
[PDF][PDF] Gold and nano-gold in medicine: overview, toxicology and perspectives.
NR Panyala, EM Peña-Méndez, J Havel - Journal of applied …, 2009 - jab.zsf.jcu.cz
… Houška J, Alberti M, Havel J: Laser ablation synthesis of phosphorus sulphides, selenides
and ternary PpSqSer clusters from various precursors. Rapid Commun Mass Spectrom 22:417…
and ternary PpSqSer clusters from various precursors. Rapid Commun Mass Spectrom 22:417…
Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer
Immune checkpoint inhibitors, which unleash a patient’s own T cells to kill tumors, are
revolutionizing cancer treatment. To unravel the genomic determinants of response to this therapy, …
revolutionizing cancer treatment. To unravel the genomic determinants of response to this therapy, …
[PDF][PDF] Tumor and microenvironment evolution during immunotherapy with nivolumab
The mechanisms by which immune checkpoint blockade modulates tumor evolution during
therapy are unclear. We assessed genomic changes in tumors from 68 patients with …
therapy are unclear. We assessed genomic changes in tumors from 68 patients with …
Artificial neural networks in medical diagnosis
…, P Vaňhara, A Hampl, J Havel - Journal of applied …, 2013 - Elsevier
… 5 becomes: (6) Δ w i j k = − η d E d w i j + μ Δ w i j k − 1 where μ is the “momentum” term
and Δw ij k-1 is the change of the weight w ij from the (k-1)- th learning cycle. The learning rate …
and Δw ij k-1 is the change of the weight w ij from the (k-1)- th learning cycle. The learning rate …
[HTML][HTML] The head and neck cancer immune landscape and its immunotherapeutic implications
Recent clinical trials have demonstrated a clear survival advantage in advanced head and
neck squamous cell carcinoma (HNSCC) patients treated with immune checkpoint blockade. …
neck squamous cell carcinoma (HNSCC) patients treated with immune checkpoint blockade. …
[PDF][PDF] Humic substances-compounds of still unknown structure: applications in agriculture, industry, environment, and biomedicine
EM Peña-Méndez, J Havel, J Patočka - J. Appl. Biomed, 2005 - jab.zsf.jcu.cz
… and Havel J.: Capillary zone electrophoresis for the separation and characterization of …
Pacheco ML and J. Havel: Capillary zone electrophoresis of humic acids from American continent…
Pacheco ML and J. Havel: Capillary zone electrophoresis of humic acids from American continent…
[PDF][PDF] Silver or silver nanoparticles: a hazardous threat to the environment and human health?
NR Panyala, EM Peña-Méndez, J Havel - Journal of applied …, 2008 - jab.zsf.jcu.cz
… Cheng D, Yang J, Zhao Y: Antibacterial materials of silver nanoparticles application in …
Zhang Y, Chen F, Zhuang J: Synthesis of silver nanoparticles via electrochemical reduction on …
Zhang Y, Chen F, Zhuang J: Synthesis of silver nanoparticles via electrochemical reduction on …
Flooding to restore connectivity of regulated, large-river wetlands: natural and controlled flooding as complementary processes along the lower Missouri River
You can always count on finding the Mississippi just where you left it last year. But the
Missouri is a tawny, restless, brawling flood. It cuts corners, runs around at night, fills itself with …
Missouri is a tawny, restless, brawling flood. It cuts corners, runs around at night, fills itself with …