[PDF][PDF] Commensal microbiota regulates skin barrier function and repair via signaling through the aryl hydrocarbon receptor

…, J Bugayev, J Horwinski, C Bradley, J Meyer… - Cell host & …, 2021 - cell.com
… We found that both male and female wild-type C57BL6/J mice could repair a barrier that was
disrupted to TEWL ~15–20 g/m2/h within 24 h (Figures S2A–S2C); therefore, we chose this …

[HTML][HTML] Temporal stability in chronic wound microbiota is associated with poor healing

M Loesche, SE Gardner, L Kalan, J Horwinski… - Journal of Investigative …, 2017 - Elsevier
Microbial burden of chronic wounds is believed to play an important role in impaired healing
and the development of infection-related complications. However, clinical cultures have …

[PDF][PDF] Strain-and species-level variation in the microbiome of diabetic wounds is associated with clinical outcomes and therapeutic efficacy

LR Kalan, JS Meisel, MA Loesche, J Horwinski… - Cell host & …, 2019 - cell.com
Chronic wounds are a major complication of diabetes associated with high morbidity and
health care expenditures. To investigate the role of colonizing microbiota in diabetic wound …

Escherichia coli ST131-H22 as a Foodborne Uropathogen

…, L Gauld, B Weaver, D Rolland, S Statham, J Horwinski… - MBio, 2018 - Am Soc Microbiol
Escherichia coli sequence type 131 (ST131) has emerged rapidly to become the most
prevalent extraintestinal pathogenic E. coli clones in circulation today. Previous investigations …

[HTML][HTML] Commensal microbiota modulate gene expression in the skin

…, C Gimblet, J Bugayev, J Horwinski… - Microbiome, 2018 - Springer
Background The skin harbors complex communities of resident microorganisms, yet little is
known of their physiological roles and the molecular mechanisms that mediate cutaneous …

Intermingled Klebsiella pneumoniae Populations Between Retail Meats and Human Urinary Tract Infections

…, H Grande, R Bigler, J Horwinski… - Clinical Infectious …, 2015 - academic.oup.com
Background. Klebsiella pneumoniae is a common colonizer of the gastrointestinal tract of
humans, companion animals, and livestock. To better understand potential contributions of …

[HTML][HTML] Antibiotic-resistant Escherichia coli from retail poultry meat with different antibiotic use claims

…, H Grande, B Weaver, K Papp, J Horwinski… - BMC microbiology, 2018 - Springer
Background We sought to determine if the prevalence of antibiotic-resistant Escherichia coli
differed across retail poultry products and among major production categories, including …

[PDF][PDF] Cutaneous leishmaniasis induces a transmissible dysbiotic skin microbiota that promotes skin inflammation

…, JS Meisel, MA Loesche, SD Cole, J Horwinski… - Cell host & …, 2017 - cell.com
Skin microbiota can impact allergic and autoimmune responses, wound healing, and anti-microbial
defense. We investigated the role of skin microbiota in cutaneous leishmaniasis and …

Topical antimicrobial treatments can elicit shifts to resident skin bacterial communities and reduce colonization by Staphylococcus aureus competitors

AJ SanMiguel, JS Meisel, J Horwinski… - Antimicrobial agents …, 2017 - Am Soc Microbiol
The skin microbiome is a complex ecosystem with important implications for cutaneous
health and disease. Topical antibiotics and antiseptics are often employed to preserve the …

[HTML][HTML] Antiseptic agents elicit short-term, personalized, and body site–specific shifts in resident skin bacterial communities

AJ SanMiguel, JS Meisel, J Horwinski, Q Zheng… - Journal of Investigative …, 2018 - Elsevier
Despite critical functions in cutaneous health and disease, it is unclear how resident skin
microbial communities are altered by topical antimicrobial interventions commonly used in …