Purpose Endometrial cancers have long been divided into estrogen-dependent type I and
the less common clinically aggressive estrogen-independent type II. Little is known about risk …

Helicobacter pylori infection is associated with a variety of clinical outcomes including gastric
cancer and duodenal ulcer disease 1 . The reasons for this variation are not clear, but the …

Breast cancer exhibits familial aggregation, consistent with variation in genetic susceptibility
to the disease. Known susceptibility genes account for less than 25% of the familial risk of …

Background: Human papillomavirus (HPV), the causal agent of cervical cancer, appears to
be involved in the etiology of cancer of the oral cavity and oropharynx. To investigate these …

Lung cancer is the most common cause of cancer death worldwide, with over one million
cases annually 1 . To identify genetic factors that modify disease risk, we conducted a genome-…

Breast cancer is the most common cancer among women. Common variants at 27 loci have
been identified as associated with susceptibility to breast cancer, and these account for ∼9…

Background Immunohistochemical markers are often used to classify breast cancer into
subtypes that are biologically distinct and behave differently. The aim of this study was to …

Stratification of women according to their risk of breast cancer based on polygenic risk scores
(PRSs) could improve screening and prevention strategies. Our aim was to develop PRSs, …

Background Previous studies have suggested that breast cancer risk factors are associated
with estrogen receptor (ER) and progesterone receptor (PR) expression status of the tumors. …

Characterized primarily by a low body-mass index, anorexia nervosa is a complex and
serious illness 1 , affecting 0.9–4% of women and 0.3% of men 2 , 3 – 4 , with twin-based …