[HTML][HTML] Ameliorative effect of fisetin on cisplatin-induced nephrotoxicity in rats via modulation of NF-κB activation and antioxidant defence
BD Sahu, AK Kalvala, M Koneru, J Mahesh Kumar… - PloS one, 2014 - journals.plos.org
Nephrotoxicity is a dose-dependent side effect of cisplatin limiting its clinical usage in the
field of cancer chemotherapy. Fisetin is a bioactive flavonoid with recognized antioxidant and …
field of cancer chemotherapy. Fisetin is a bioactive flavonoid with recognized antioxidant and …
Refunctionalization of decellularized organ scaffold of pancreas by recellularization: whole organ regeneration into functional pancreas
…, Y Kameshwari, N Rangaraj, J Mahesh Kumar… - Tissue Engineering and …, 2021 - Springer
Background: Tissue engineering centers on creating a niche similar to the natural one, with
a purpose of developing an organ construct. A natural scaffold can replace none while …
a purpose of developing an organ construct. A natural scaffold can replace none while …
Effects of fisetin on hyperhomocysteinemia-induced experimental endothelial dysfunction and vascular dementia
…, J Mahesh Kumar, B Dinesh Kumar… - Canadian journal of …, 2017 - cdnsciencepub.com
This study was designed to investigate the effects of fisetin (FST) on hyperhomocysteinemia
(HHcy)-induced experimental endothelial dysfunction (ED) and vascular dementia (VaD) in …
(HHcy)-induced experimental endothelial dysfunction (ED) and vascular dementia (VaD) in …
Strobilocercus fasciolaris infection with hepatic sarcoma and gastroenteropathy in a Wistar colony
JM Kumar, PL Reddy, V Aparna, G Srinivas… - Veterinary …, 2006 - Elsevier
Tapeworm cysts were identified in liver of Wistar rats and it induced fibrosarcoma in liver
and gastroenteropathy in stomach and intestine. The tapeworm larva was confirmed as …
and gastroenteropathy in stomach and intestine. The tapeworm larva was confirmed as …
Impaired GABAergic and glutamatergic neurometabolic activity in aged mice brain as measured by 1H‐[13C]‐NMR spectroscopy
…, P Veeraiah, M Shameem, J Mahesh Kumar… - The FASEB …, 2021 - Wiley Online Library
… Shameem contributed to animal experiment data acquisition and analysis; AB Patel and J.
Mahesh Kumar contributed to new reagents and analytic tools; AB Patel, K. Saba and P. …
Mahesh Kumar contributed to new reagents and analytic tools; AB Patel, K. Saba and P. …
[HTML][HTML] Phenyl 1, 2, 3-triazole-thymidine ligands stabilize G-quadruplex DNA, inhibit DNA synthesis and potentially reduce tumor cell proliferation over 3′-azido …
J Mahesh Kumar, MM Idris, G Srinivas… - PLoS …, 2013 - journals.plos.org
Triazoles are known for their non-toxicity, higher stability and therapeutic activity. Few
nucleoside (L1, L2 and L3) and non-nucleoside 1,2,3-triazoles (L4–L14) were synthesised using …
nucleoside (L1, L2 and L3) and non-nucleoside 1,2,3-triazoles (L4–L14) were synthesised using …
Capsaicin, the pungent principle of peppers, ameliorates alcohol-induced acute liver injury in mice via modulation of matrix metalloproteinases
…, M Kuncha, J Mahesh Kumar… - Canadian journal of …, 2018 - cdnsciencepub.com
Alcohol, the most common cause for hepatic injury, may further deteriorate the hepatic
tissue when left unattended. Capsaicin, the pungent principle of chilli peppers, possesses …
tissue when left unattended. Capsaicin, the pungent principle of chilli peppers, possesses …
Anticancer Activity of Half‐Sandwich RhIII and IrIII Metalla‐Prisms Containing Lipophilic Side Chains
… All biological studies suggest that the rhodium derivative [3][CF 3 SO 3 ] 6 possesses
excellent activities, not only in vitro but also in vivo in tumour‐induced C57L6/J mice. …
excellent activities, not only in vitro but also in vivo in tumour‐induced C57L6/J mice. …
Ang II induce kidney damage by recruiting inflammatory cells and up regulates PPAR gamma and Renin 1 gene: effect of β carotene on chronic renal damage
…, T Avinash Raj, J Mahesh Kumar - Journal of thrombosis …, 2013 - Springer
Antioxidants are widely used for prevention of diseases associated with oxidative stress and
ischemic disorder. We investigated the hypothesis of antioxidants (α-tocopherol and β-…
ischemic disorder. We investigated the hypothesis of antioxidants (α-tocopherol and β-…
Engineered reversal of drug resistance in cancer cells—metastases suppressor factors as change agents
…, SK Pore, R Banerjee, J Mahesh Kumar… - Nucleic acids …, 2013 - academic.oup.com
Building molecular correlates of drug resistance in cancer and exploiting them for
therapeutic intervention remains a pressing clinical need. To identify factors that impact drug …
therapeutic intervention remains a pressing clinical need. To identify factors that impact drug …